Anti-Angiocidin (S5a, RPN10a, Mcb1)

Anti-Angiocidin (S5a, RPN10a, Mcb1)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
A2292-23.100 100 µg - -

3 - 19 business days*

Angiocidin (also S5a, RPN10a and Mcb1) is a 41kD (predicted) member of the proteosome subunit S5A... more
Product information "Anti-Angiocidin (S5a, RPN10a, Mcb1)"
Angiocidin (also S5a, RPN10a and Mcb1) is a 41kD (predicted) member of the proteosome subunit S5A family of proteins. It runs anomalously in SDS-page at 55kD. Intracellularly, Angiocidin is a component of the 26S proteosome that degrades ubiquitinated proteins. Extracellularly, it inhibits angiogenesis by binding to collagen and beta 1 integrins. Mouse Angiocidin is 376aa in length. It contains a vWF-A domain (aa5-188), a beta 1 interacting site (aa86-105) and two ubiquitin-interacting motifs (aa211-230 and 282-301). There are four splice variants. Three show a GlyGluArg insertion after Glu254, with two of these showing an additional three aa substitution for aa255-376, and a 45aa substitution for aa321-376, respectfully. A fourth shows a 51aa substitution for aa299-376. Over aa1-254, mouse Angiocidin shares > 99% aa identity with rat and human Angiocidin. , , Applications: , Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: ELISA: 0.5-1.0ug/ml, Western Blot: 1.0ug/ml , Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized and reconstituted products are stable for 12 months after receipt at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Keywords: Anti-Psmd4, Anti-Multiubiquitin chain-binding protein, Anti-26S proteasome regulatory subunit S5A, Anti-26S proteasome regulatory subunit RPN10, Anti-26S proteasome non-ATPase regulatory subunit 4
Supplier: United States Biological
Supplier-Nr: A2292-23


Application: ELISA, WB
Antibody Type: Polyclonal
Conjugate: No
Host: Goat
Reactivity: Mouse
Immunogen: Recombinant mouse Angiocidin isoform A aa2-254, O35226 (E. coli).
Format: Affinity Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Our products are for laboratory research use only: Not for administration to humans!
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