Anti-Androgen Receptor (AR, AIS, Androgen receptor, DHTR, Dihydrotestosterone Receptor, HUMARA, HYSP

Anti-Androgen Receptor (AR, AIS, Androgen receptor, DHTR, Dihydrotestosterone Receptor, HUMARA, HYSP
Item number Size Datasheet Manual SDS Delivery time Quantity Price
A2281-01D.100 100 µg - -

3 - 19 business days*

916.00€
 
The Androgen Receptor (Androgen R) is a 90kD steroid hormone receptor that is critical for the... more
Product information "Anti-Androgen Receptor (AR, AIS, Androgen receptor, DHTR, Dihydrotestosterone Receptor, HUMARA, HYSP"
The Androgen Receptor (Androgen R) is a 90kD steroid hormone receptor that is critical for the development and function of the male reproductive system. Androgen R binding to testosterone or 5alpha-dihydrotestosterone (DHT) triggers receptor dimerization followed by translocation to the nucleus where it promotes transcription of androgen responsive genes. Multiple polymorphisms in Androgen R are linked to the development of prostate cancer. The ligand binding domain of human Androgen R (aa661-920) shares 100% aa sequence identity with mouse and rat Androgen R. Applications: Suitable for use in ELISA and Flow Cytometry. Other applications not tested. Recommended Dilution: Flow Cytometry: 25ug/ml, 10ul labels 1-2.5 x 10e5 cells in a total reaction volume < 200ul., Direct ELISA: 0.5-1ug/ml. The detection limit is ~1ng/well., Optimal dilutions to be determined by the researcher. Hybridoma: Mouse myeloma cells with B cells obtained from a mouse immunized with purified, E. coli-derived, recombinant human Androgen R (aa661-920). Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Keywords: Anti-Dihydrotestosterone receptor, Anti-Nuclear receptor subfamily 3 group C member 4
Supplier: United States Biological
Supplier-Nr: A2281-01D

Properties

Application: ELISA, FC
Antibody Type: Monoclonal
Clone: 9L802
Conjugate: No
Host: Mouse
Species reactivity: human
Immunogen: E. coli-derived, recombinant human Androgen R (aa661-920, Accession # P10275).
Format: Affinity Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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