Anti-AGRP

Anti-AGRP
Item number Size Datasheet Manual SDS Delivery time Quantity Price
NSJ-RQ4011 100 µg - -

3 - 10 business days*

755.00€
 
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Agouti-related protein (AgRP), also called... more
Product information "Anti-AGRP"
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Agouti-related protein (AgRP), also called agouti-related peptide, is a neuropeptide produced in the brain by the AgRP/NPY neuron. In humans, the agouti-related peptide is encoded by the AGRP gene. This gene encodes an antagonist of the melanocortin-3 and melanocortin-4 receptor. It appears to regulate hypothalamic control of feeding behavior via melanocortin receptor and/or intracellular calcium regulation, and thus plays a role in weight homeostasis. Mutations in this gene have been associated with late on-set obesity. Protein function: Plays a role in weight homeostasis. Involved in the control of feeding behavior through the central melanocortin system. Acts as alpha melanocyte-stimulating hormone antagonist by inhibiting cAMP production mediated by stimulation of melanocortin receptors within the hypothalamus and adrenal gland. Has very low activity with MC5R. Is an inverse agonist for MC3R and MC4R being able to suppress their constitutive activity. It promotes MC3R and MC4R endocytosis in an arrestin-dependent manner. [The UniProt Consortium]
Keywords: Anti-Agrp, Anti-Agrt, Anti-Agouti-related protein, AGRP Antibody
Supplier: NSJ Bioreagents
Supplier-Nr: RQ4011

Properties

Application: IHC (paraffin), ELISA
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, mouse, rat
Immunogen: A recombinant mouse partial protein corresponding to amino acids S82-T131 was used as the immunogen for the AGRP antibody.
Format: Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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