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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
A1059-59F2.100 | 100 µg | - | - |
3 - 19 business days* |
662.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Agrin is an essential extracellular matrix component which promotes clustering of nicotinic... more
Product information "Anti-AGR2 (Anterior Gradient Protein 2 Homolog, AG-2, hAG-2, HPC8, Secreted Cement Gland Protein XAG"
Agrin is an essential extracellular matrix component which promotes clustering of nicotinic acetylcholine receptors (nAChRs) and other proteins during development at the neuromuscular junction. Agrin, MuSK and Rapsyn are all essential components for AChR aggregation, through an unknown mechanism. The C-terminal region of agrin is released into the medium, interacts with receptors on the muscle surface and induces AChR aggregation. The central region contains two O-linked glycosylation sites and a domain homologous to domain III of laminin. The N-terminal region anchors agrin to the extracellular matrix via other basal membrane components. This region also contains a protease inhibitor domain and glycosaminoglycan attachment sites, increasing the predicted MW from 200kD to ~600kD. Applications: Suitable for use in Western Blot, Immunohistochemistry and Immunoprecipitation . Other applications not tested. Recommended Dilution: Western Blot: 1:100, Immunohistochemistry (formalin fixed paraffin embedded): 1:100, Immunohistochemistry: Frozen, Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Keywords: | Anti-Anterior gradient protein 2 homolog, Anti-Secreted cement gland protein XAG-2 homolog |
Supplier: | United States Biological |
Supplier-Nr: | A1059-59F2 |
Properties
Application: | IHC, IP, WB |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human, mouse |
Immunogen: | Synthetic peptides corresponding to aa55-72 (TQTYEEALYKSKTSNKPL) of human AGR2, (Genbank accession no. NP_006399.1.) |
Format: | Affinity Purified |
Database Information
KEGG ID : | K20356 | Matching products |
UniProt ID : | O95994 | Matching products |
Gene ID | GeneID 10551 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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