Anti-ADPN (Adiponutrin, Patatin-like Phospholipase Domain containing 3)

Anti-ADPN (Adiponutrin, Patatin-like Phospholipase Domain containing 3)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
A0901-25A.100 100 µg - -

3 - 19 business days*

742.00€
 
Human ADPN (Adiponutrin, also PNPLA3 and patatin-like phospholipase domain-containing protein 3)... more
Product information "Anti-ADPN (Adiponutrin, Patatin-like Phospholipase Domain containing 3)"
Human ADPN (Adiponutrin, also PNPLA3 and patatin-like phospholipase domain-containing protein 3) is a 53kD member of the PNPLA family of phospholipase A2 enzymes. It is expressed in white adipocytes. Adiponutrin is elevated in response to insulin and appears to act not as a phospholipase, but a molecule involved in anabolic pathways. ADPN is likely to be a type II transmembrane protein that is 481aa in length. It contains one patatin domain (aa10-179) that is associated with in vitro enzyme activity and a transmembrane segment between aa42-62. There appear to be two splice variants. One shows a four aa deletion of aa59-62 and a second shows an alternate start site at Met379. Over aa 160-349, human ADPN shares 61% aa identity with mouse Adiponutrin. , , Applications: , Suitable for use in ELISA, Western Blot, and Immunohistochemistry. Other applications not tested. Recommended Dilution: ELISA: 0.5-1.0ug/ml, Western Blot: 1.0ug/ml, Immunohistochemistry: 10ug/ml, Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized powder may be stored at 4°C for short-term only. Reconstitute to nominal volume by adding sterile 40-50% glycerol and store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Keywords: EC=2.3.1.-, EC=3.1.1.3, Anti-PNPLA3, Anti-iPLA2-epsilon, Anti-Acylglycerol O-acyltransferase, Anti-Calcium-independent phospholipase A2-epsilon, Anti-Patatin-like phospholipase domain-containing protein 3
Supplier: United States Biological
Supplier-Nr: A0901-25A

Properties

Application: ELISA, IHC, WB
Antibody Type: Polyclonal
Conjugate: No
Host: Sheep
Reactivity: Human
Immunogen: Recombinant human ADPN, aa160-349 (E. coli).
Format: Affinity Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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