Anti-ADAMTS5

Anti-ADAMTS5
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ATA-HPA005661.25 25 µl -

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166.00€
ATA-HPA005661.100 100 µl -

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370.00€
 
Protein function: Metalloproteinase that plays an important role in connective tissue... more
Product information "Anti-ADAMTS5"
Protein function: Metalloproteinase that plays an important role in connective tissue organization, development, inflammation, arthritis, and cell migration. ADAMTS5 is an extracellular matrix (ECM) degrading enzyme that show proteolytic activity toward the hyalectan group of chondroitin sulfate proteoglycans (CSPGs) including aggrecan, versican, brevican and neurocan (PubMed:16133547, PubMed:18992360). Cleavage within the hyalectans occurs at Glu-Xaa recognition motifs. Plays a role in embryonic development, including limb and cardiac morphogenesis, and skeletal muscle development through its versican remodeling properties. Participates in development of brown adipose tissue and browning of white adipose tissue. Plays an important role for T-lymphocyte migration from draining lymph nodes following viral infection. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 85% and to rat: 84%
Keywords: Anti-ADMP-2, Anti-ADAMTS5, Anti-ADAM-TS5, Anti-ADAMTS-5, Anti-ADAMTS11, Anti-ADAMTS-11, Anti-ADAM-TS 5, Anti-ADAM-TS 11, EC=3.4.24.-, Anti-Aggrecanase-2, Anti-A disintegrin and metalloproteinase with thrombospondin motifs 5
Supplier: Atlas Antibodies
Supplier-Nr: HPA005661

Properties

Application: IHC
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Human
Immunogen: Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: KGLVQNIDQL YSGGGKVGYL VYAGGRRFLL DLERDGSVGI AGFVPAGGGT SAPWRHRSHC FYRGTVDGSP RSLAVFDLCG GLDGFFAVKH ARYTLKPLLR GPWAEEEKGR VYGDGS (ATA-APrEST85176)

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: +20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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