Anti-Acidic Cytokeratin, clone AE1

Item number Size Datasheet Manual SDS Delivery time Quantity Price
NSJ-V2328SAF-100UG 100 µg - -

3 - 10 business days*

752.00€
 
1 mg/ml in sterile PBS, BSA free, sodium azide free. Cytokeratins, also called keratins or simply... more
Product information "Anti-Acidic Cytokeratin, clone AE1"
1 mg/ml in sterile PBS, BSA free, sodium azide free. Cytokeratins, also called keratins or simply CKs, are a family of fibrous structural proteins and a major structural component in the outer layer of human skin, as well as hair and nails. áThere are 20 human epithelial keratins which can be divided into two subfamiles: acidic and basic (more recent human genone sequencing has identified an additional 20 members). The formation of cytokeratin intermediate filaments requires the pairing of at least one acidic and one basic subfamily member. Members of the same cytokeratin subfamily share extended sequence homology while members of different subfamilies show only limited sequence homology.This antibody is specific for the 56.5kDa (CK10), 50kDa (CK14), 50kDa (CK15), 48kDa (CK16), and 40kDa (CK19) keratins of the acidic (Type I or LMW) subfamily. Many studies have shown the usefulness of CKs as markers in cancer research and tumor diagnosis, as epithelial tumors generally maintain the same CK expression patterns as their counterpart normal tissue. Clone AE1 is commonly used with clone AE3 as a pan cytokeratin antibody cocktail (Cat No V2330).
Keywords: Anti-KPP, Anti-K10, Anti-KRT10, Anti-CK-10, Anti-Keratin-10, Anti-Cytokeratin-10, Anti-Keratin, type I cytoskeletal 10, Acidic Cytokeratin Antibody
Supplier: NSJ Bioreagents
Supplier-Nr: V2328SAF

Properties

Application: WB, FC, IHC, IF
Antibody Type: Monoclonal
Clone: AE1
Conjugate: No
Host: Mouse
Species reactivity: human, monkey, bovine, dog, rabbit, mouse, rat, chicken, turtle
Immunogen: Solubilized keratin extract from human stratum corneum
Format: Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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