Anti-ABL2

Anti-ABL2
Item number Size Datasheet Manual SDS Delivery time Quantity Price
029933.100 100 µl - -

3 - 19 business days*

477.00€
 
ABL2 (ARG, Abl-related gene), together with c-Abl, forms the Abl family of mammalian non-receptor... more
Product information "Anti-ABL2"
ABL2 (ARG, Abl-related gene), together with c-Abl, forms the Abl family of mammalian non-receptor tyrosine kinases. ABL2 and c-Abl share 89%, 90 and 93% identity in their SH3, SH2 and tyrosine domain, but only 29% identity in the carboxy-terminal half. The human c-Abl and ABL2 genes are expressed ubiquitously. ABL2 had been detected predominantly in the cytoplasm, whereas c-Abl shows both cytoplasmic and nuclear localization. c-Abl is involved in two different chromosomal translocations present in human leukemias, which generate Bcr-Abl and TEL-Abl. Recently, TEL-ARG fusion transcripts have also been identified in acute myeloid leukemias (AML). The Abl family kinases may also interact with receptor tyrosine signaling pathways and regulate cellular function such as cell cycle progression, gene transcription and organization of the actin cytoskeletons in neurons. Applications: Western Bloting: 1:500-1:2000., Immunofluorescence: 1:200-1:1000., ELISA: Suggested dilution 1:10000., Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Keywords: Anti-ABLL, Anti-ABL2, EC=2.7.10.2, Anti-Tyrosine-protein kinase ARG, Anti-Abelson-related gene protein, Anti-Abelson tyrosine-protein kinase 2, Anti-Abelson murine leukemia viral oncogene homolog 2
Supplier: United States Biological
Supplier-Nr: 029933

Properties

Application: ELISA, WB
Antibody Type: Monoclonal
Clone: 13B11
Conjugate: No
Host: Mouse
Reactivity: Human, Mouse
Immunogen: Purified recombinant fragment of ABL2 expressed in E. coli.

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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