Anti-ABL1

Anti-ABL1
Item number Size Datasheet Manual SDS Delivery time Quantity Price
029931.100 100 µl - -

3 - 19 business days*

477.00€
 
ABL1: c-abl oncogene 1, receptor tyrosine kinase. The ABL1 protooncogene encodes a cytoplasmic... more
Product information "Anti-ABL1"
ABL1: c-abl oncogene 1, receptor tyrosine kinase. The ABL1 protooncogene encodes a cytoplasmic and nuclear protein tyrosine kinase that has been implicated in processes of cell differentiation, cell division, cell adhesion, and stress response. Activity of c-Abl protein is negatively regulated by its SH3 domain, and deletion of the SH3 domain turns ABL1 into an oncogene. The t(9,22) translocation results in the head-to-tail fusion of the BCR (MIM:151410) and ABL1 genes present in many cases of chronic myelogeneous leukemia. The DNA-binding activity of the ubiquitously expressed ABL1 tyrosine kinase is regulated by CDC2-mediated phosphorylation, suggesting a cell cycle function for ABL1. The ABL1 gene is expressed as either a 6- or 7-kb mRNA transcript, with alternatively spliced first exons spliced to the common exons 2-11. Applications: Western Bloting: 1:500-1:2000., ELISA: Suggested dilution 1:10000., Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Keywords: Anti-ABL, Anti-ABL1, Anti-p150, EC=2.7.10.2, Anti-Proto-oncogene c-Abl, Anti-Tyrosine-protein kinase ABL1, Anti-Abelson tyrosine-protein kinase 1, Anti-Abelson murine leukemia viral oncogene homolog 1
Supplier: United States Biological
Supplier-Nr: 029931

Properties

Application: ELISA, WB
Antibody Type: Monoclonal
Clone: 13B9
Conjugate: No
Host: Mouse
Reactivity: Human
Immunogen: Purified recombinant fragment of ABL1 (aa577-650) expressed in E. coli.

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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