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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
NSJ-F44284-0.08ML | 80 µl | - | - |
3 - 10 business days* |
326.00€
|
||
NSJ-F44284-0.4ML | 400 µl | - | - |
3 - 10 business days* |
702.00€
|
In 1X PBS, pH 7.4, with 0.09% sodium azide. ABCG2 is a membrane-associated protein included in... more
Product information "Anti-ABCG2"
In 1X PBS, pH 7.4, with 0.09% sodium azide. ABCG2 is a membrane-associated protein included in the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. Alternatively referred to as a breast cancer resistance protein, this protein functions as a xenobiotic transporter which may play a major role in multi-drug resistance. It likely serves as a cellular defense mechanism in response to mitoxantrone and anthracycline exposure. Significant expression of this protein has been observed in the placenta, which may suggest a potential role for this molecule in placenta tissue. Protein function: High-capacity urate exporter functioning in both renal and extrarenal urate excretion. Plays a role in porphyrin homeostasis as it is able to mediates the export of protoporhyrin IX (PPIX) both from mitochondria to cytosol and from cytosol to extracellular space, and cellular export of hemin, and heme. Xenobiotic transporter that may play an important role in the exclusion of xenobiotics from the brain. Appears to play a major role in the multidrug resistance phenotype of several cancer cell lines. Implicated in the efflux of numerous drugs and xenobiotics: mitoxantrone, the photosensitizer pheophorbide, camptothecin, methotrexate, azidothymidine (AZT), and the anthracyclines daunorubicin and doxorubicin. [The UniProt Consortium]
Keywords: | Anti-ABCP, Anti-CD338, Anti-ABCG2, Anti-CDw338, Anti-Urate exporter, Anti-Breast cancer resistance protein, Anti-ATP-binding cassette sub-family G member 2, Anti-Mitoxantrone resistance-associated protein, ABCG2 Antibody |
Supplier: | NSJ Bioreagents |
Supplier-Nr: | F44284 |
Properties
Application: | WB, IF, FC, IHC, ELISA |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human |
Immunogen: | A portion of amino acids 305-335 from the human protein was used as the immunogen for this ABCG2 antibody. |
Format: | Purified |
Database Information
KEGG ID : | K05681 | Matching products |
UniProt ID : | Q9UNQ0 | Matching products |
Gene ID | GeneID 9429 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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