Anti-ABCA4 (ATP Binding Cassette Sub-family A Member 4, ATP-binding Cassette Sub-family A (ABC1) Mem

Anti-ABCA4 (ATP Binding Cassette Sub-family A Member 4, ATP-binding Cassette Sub-family A (ABC1) Mem
Item number Size Datasheet Manual SDS Delivery time Quantity Price
A0004-02D2.100 100 µg - -

3 - 19 business days*

414.00€
 
The membrane-associated protein encoded by this gene is a member of the superfamily of... more
Product information "Anti-ABCA4 (ATP Binding Cassette Sub-family A Member 4, ATP-binding Cassette Sub-family A (ABC1) Mem"
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. This protein is a retina-specific ABC transporter with N-retinylidene-PE as a substrate. It is expressed exclusively in retina photoreceptor cells, indicating the gene product mediates transport of an essental molecule across the photoreceptor cell membrane. Mutations in this gene are found in patients diagnosed with Stargardt disease, a form of juvenile-onset macular degeneration. Mutations in this gene are also associated with retinitis pigmentosa-19, cone-rod dystrophy type 3, early-onset severe retinal dystrophy, fundus flavimaculatus, and macular degeneration age-related 2. Applications: Suitable for use in ELISA. Other Applications not tested. Recommended Dilutions: ELISA: 1:32,000, Optimal dilutions to be determined by the researcher, Control Peptide: A0004-02D2-P, Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Keywords: Anti-RIM protein, Anti-RIM ABC transporter, Anti-Stargardt disease protein, Anti-ATP-binding cassette sub-family A member 4, Anti-Retinal-specific ATP-binding cassette transporter
Supplier: United States Biological
Supplier-Nr: A0004-02D2

Properties

Application: ELISA
Antibody Type: Polyclonal
Conjugate: No
Host: Goat
Reactivity: Human
Immunogen: Synthetic peptide, EPECPGPQLNTGTQ, from the internal region of human ABCA4.
Format: Affinity Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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