Anti-15-hydroxy Prostaglandin Dehydrogenase

Anti-15-hydroxy Prostaglandin Dehydrogenase
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay160615-1 1 each -

5 - 10 business days*

324.00€
 
NAD+-dependent 15-hydroxy PGDH catalyzes the oxidation of prostaglandins to 15-keto metabolites,... more
Product information "Anti-15-hydroxy Prostaglandin Dehydrogenase"
NAD+-dependent 15-hydroxy PGDH catalyzes the oxidation of prostaglandins to 15-keto metabolites, which have greatly reduced biological activity. Human NAD+-dependent 15-hydroxy PGDH is a 266 amino acid protein with a molecular weight of 29 kDa and is expressed in multiple tissues including lung, placenta, and kidney. The enzyme belongs to a large family of short-chain alcohol dehydrogenases, which exhibit amino acid identity ranging from 15-30%. An NADP+-dependent 15-hydroxy PGDH, which is also part of this enzyme family, exhibits only 20% amino acid identity to the NAD+-dependent enzyme. The peptide used as the antigen for preparation of the 15-hydroxy PGDH antibody is highly conserved across several species (see above), but has only minor homology to other proteins within the short-chain alcohol dehydrogenase family of enzymes (only the alanine and glycine at the N-terminus of the sequence appear to be conserved). Cayman's 15-hydroxy PGDH Polyclonal Antibody can be used for Western blot applications. The antibody recognizes 15-hydroxy PGDH at 29 kDa from human, baboon, and mouse samples. Synonyms: 15-hydroxy PGDH. Immunogen: Synthetic peptide from an internal region of human 15-hydroxy PGDH. Formulation: Peptide Affinity-purified IgG. Storage Buffer: PBS, pH 7.2, with 50% glycerol and 0.02% sodium azide. Host: Rabbit. Applications: WB. UniProt Accession #: P15428. Origin: Animal/Rabbit.
Keywords: Anti-PGDH1, Anti-15-PGDH, Anti-15-PGDH, Anti-Prostaglandin dehydrogenase 1, Anti-Prostaglandin dehydrogenase 1, Anti-Short chain dehydrogenase/reductase family 36C member 1, Anti-Short chain dehydrogenase/reductase family 36C member 1, Anti-15-hydroxypros
Supplier: Cayman Chemical
Supplier-Nr: 160615

Properties

Application: WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Human, Bovine, Guinea Pig, Baboon
Immunogen: Synthetic peptide from an internal region of human 15-hydroxy PGDH
Format: Solid

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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