Human SSBP1 Antibody Pair

Human SSBP1 Antibody Pair
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ABS-ES-1502.1 1 set (100 µg (capture) + 100 µg (detection)) - -

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1,080.00€
 
Protein function: Binds preferentially and cooperatively to pyrimidine rich single-stranded DNA... more
Product information "Human SSBP1 Antibody Pair"
Protein function: Binds preferentially and cooperatively to pyrimidine rich single-stranded DNA (ss-DNA) (PubMed:21953457, PubMed:23290262). In vitro, required to maintain the copy number of mitochondrial DNA (mtDNA) and plays crucial roles during mtDNA replication that stimulate activity of the replisome components POLG and TWNK at the replication fork (PubMed:21953457, PubMed:12975372, PubMed:26446790, PubMed:15167897). Promotes the activity of the gamma complex polymerase POLG, largely by organizing the template DNA and eliminating secondary structures to favor ss-DNA conformations that facilitate POLG activity (PubMed:26446790, PubMed:21953457). In addition it is able to promote the 5'-3' unwinding activity of the mtDNA helicase TWNK (PubMed:12975372). May also function in mtDNA repair (PubMed:23290262). [The UniProt Consortium]
Keywords: Anti-SSBP, Anti-SSBP1, Anti-MtSSB, Anti-Mt-SSB, Anti-PWP1-interacting protein 17, Anti-Single-stranded DNA-binding protein, mitochondrial
Supplier: Absea
Supplier-Nr: ES-1502

Properties

Application: ELISA
Antibody Type: Monoclonal
Host: Mouse/Mouse
Species reactivity: human
Format: Solution

Handling & Safety

Storage: -20°C (avoid repeat freezing and thawing cycles)
Shipping: -20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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