Antibody Panels

A700-016 Rabbit anti-CD3E Recombinant Monoclonal Antibody [BL-298-5D12], A700-044 Rabbit anti-CD8 alpha Recombinant Monoclonal Antibody [BLR044F], A500-017A Mouse anti-CD20 Monoclonal Antibody, Purified [L26]

PathPlex Panel 4 identifies total T-cells (CD3), cytotoxic T-cells (CD8) and regulatory T-cells (FoxP3) within the context of the tumor microenvironment. Antigen presenting cells such as macrophages (CD68) or tumor cells (cytokeratin) express immune checkpoint ligands such as PD-L1 which inhibits the ability of...

PathPlex Panel 5 identifies total T-cells (CD3), cytotoxic T-cells (CD8) and cells expressing the immune checkpoint ligand PD-L1 within the context of the tumor microenvironment. PD-L1 can be expressed on antigen presenting cells such as macrophages (CD68) or tumor cells (cytokeratin). Ki-67 is a proliferation...

PathPlex Panel 6 identifies total T-cells (CD3) and cytotoxic T-cells (CD8) and activated cytotoxic T-cells (Granzyme B) within the tumor microenvironment. The inclusion of multiple tumor cell makers (cytokeratin, Sox10 and Ki-67) provides flexibility across multiple tumor types.

PathPlex Panel 7 identifies total cytotoxic T-cells (CD8), T-helper cells (CD4), memory T-cells (CD45RO) and regulatory T-cells (FoxP3) within the context of the tumor microenvironment. Tumor cells are identified by cytokeratin.

PathPlex Panel 8 identifies total T-cells (CD3), T-helper cells (CD4), cytotoxic T-cells (CD8) and regulatory T-cells (FoxP3) within the tumor microenvironment. Lag3 is a checkpoint inhibitor which identifies exhausted T-cells. Tumor cells are identified by cytokeratin.

Each antibody in the NLRP3 Inflammasome Mouse Antibodies Starter Set has been thoroughly validated in KO experimental setup and detects endogenous levels of its target protein: AG-20B-0014 Anti-NLRP3/NALP3, mAb (Cryo-2) 25 µg, AG-20B-0042 Anti-Caspase-1 (p20) (mouse), mAb (Casper-1) 25 µg, AG-25B-0006 Anti-Asc, pAb...

The 25-OH Vitamin D3 Matched Antibody Pair is specific to 25-OH Vitamin D3 and has been demonstrated through ELISA. It does not cross-react with Vitamin D3, Vitamin D2, and 25-OH Vitamin D2. This kit includes capture and detection antibodies. 25-Hydroxyvitamin D3 is produced in the liver by 25-hydroxylation of...

Histone H3 is one of the DNA-binding proteins found in the chromatin of all eukaryotic cells. H3 along with four core histone proteins binds to DNA forming the structure of the nucleosome. Histones play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. Histone H3 has...

Histone H3 is one of the DNA-binding proteins found in the chromatin of all eukaryotic cells. H3 along with four core histone proteins binds to DNA forming the structure of the nucleosome. Histones play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. Histone H3 has...

Histone H3 is one of the DNA-binding proteins found in the chromatin of all eukaryotic cells. H3 along with four core histone proteins binds to DNA forming the structure of the nucleosome. Histones play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. Histone H3 has...

The TUNEL assay has been commonly used as a detection method for identifying apoptotic cells. While useful, it can also yield highly variable results as some non-apoptotic nuclei showing high levels of RNA synthesis/splicing can also be labeled by TUNEL technique. Cleavage of Caspase 3 and PARP (Poly (ADP-ribose)...