NEDP1 [SENP8] (human) (rec.) (His)

NEDP1 [SENP8] (human) (rec.) (His)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
SBB-DE0025-C050 50 µg - -

3 - 9 business days*

278.00€
 
NEDP1 is a deconjugating enzyme with specificity towards NEDDylated substrates. NEDP1... more
Product information "NEDP1 [SENP8] (human) (rec.) (His)"
NEDP1 is a deconjugating enzyme with specificity towards NEDDylated substrates. NEDP1 discriminates between ubiquitinated and NEDDylated targets, despite similar C-terminal regions. NEDP1 is a protease which hydrolyzes the isopeptide bond between the C-terminus of NEDD8 and the respective lysine of the substrate protein to which the NEDD8 is covalently bound. NEDP1 is important in regulating cullin associated ubiquitin ligase enzymes such as those of the SCF (Skp-Cullin-Fbox) family and subsequently, it is important in regulating cell cycle progression and other biological functions.
Keywords: NEDD8-specific Protease 1, Sentrin-specific Protease 8, Deneddylase-1, Sentrin/SUMO-specific Protease SENP8, DEN1, PRSC2
Supplier: South Bay Bio
Supplier-Nr: DE0025

Properties

Application: Assays
Conjugate: No
Host: E.coli
Species reactivity: human
MW: 27 kD
Purity: >95%
Format: Liquid

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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