Products from Indigo Biosciences

Indigo

Indigo Biosciences, Inc. was founded in 2005 in State College, PA by Dr. Jack Vanden Heuvel and Dr. Blake Peterson. It remains a privately held biosciences company offering products and services focused on nuclear receptors, which comprise a major class of therapeutic drug targets. The company’s two founders leveraged their collective expertise’s in nuclear receptor biology, toxicology, medicinal chemistry and molecular biology to establish the core platform technology of the company.

More information at: indigobiosciences.com

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RXRbeta (human) Reporter Assay Kit
RXRbeta (human) Reporter Assay Kit

Item number: IB-IB00811

This nuclear receptor assay system utilizes proprietary non-human cells engineered to provide constitutive, high-level expression of the human retinoid X receptor beta (NR2B2), a ligand-dependent transcription factor commonly referred to as RXRB or RXRbeta. INDIGO's reporter cells include the luciferase reporter...
Keywords: RXRB, NR2B2, Retinoid X receptor beta, Retinoic acid receptor RXR-beta, Nuclear receptor subfamily 2 group B member 2
Application: Functional activity screening
Reactivity: Human
From 1,161.00€ *
Review
RXRgamma (human) Reporter Assay Kit
RXRgamma (human) Reporter Assay Kit

Item number: IB-IB00821

This nuclear receptor assay system utilizes proprietary non-human cells engineered to provide constitutive, high-level expression of the human retinoid X receptor gamma (NR2B3), a ligand-dependent transcription factor commonly referred to as RXRG or RXRgamma. INDIGO's reporter cells include the luciferase reporter...
Keywords: RXRG, NR2B3, Retinoid X receptor gamma, Retinoic acid receptor RXR-gamma, Nuclear receptor subfamily 2 group B member 3
Application: Functional activity screening
Reactivity: Human
From 1,161.00€ *
Review
RXRalpha (human) Reporter Assay Kit
RXRalpha (human) Reporter Assay Kit

Item number: IB-IB00801

This nuclear receptor assay system utilizes proprietary non-human cells engineered to provide constitutive, high-level expression of the human retinoid X receptor alpha (NR2B1), a ligand-dependent transcription factor commonly referred to as RXRA or RXRalpha. INDIGO's reporter cells include the luciferase reporter...
Keywords: RXRA, NR2B1, Retinoid X receptor alpha, Retinoic acid receptor RXR-alpha, Nuclear receptor subfamily 2 group B member 1
Application: Functional activity screening
Reactivity: Human
From 1,161.00€ *
Review
FXR (mouse) Reporter Assay Kit
FXR (mouse) Reporter Assay Kit

Item number: IB-M00601-32

This nuclear receptor assay system utilizes proprietary non-human mammalian cells engineered to provide constitutive, high-level expression of human farnesoid X receptor (NR1H4), a ligand-dependent transcription factor commonly referred to as FXR. INDIGO's reporter cells include the luciferase reporter gene...
Keywords: Bar, Nr1h4, Bile acid receptor, Farnesol receptor HRR-1, RXR-interacting protein 14, Farnesoid X-activated receptor,...
Application: Functional activity screening
Reactivity: Mouse
From 1,161.00€ *
Review
PPAR (human) Reporter Assays Panel
PPAR (human) Reporter Assays Panel

Item number: IB-IB00131-32P

INDIGO's panel of PPAR reporter assays utilizes non-human mammalian cells engineered to express human peroxisome proliferator-activated receptors: PPARalpha (NR1C1), PPARdelta (NR1C2), or PPARgamma (NR1C3), all ligand-dependent transcription factors that are commonly referred to as PPARalpha, PPARdelta and...
Keywords: PPARalpha (NR1C1), PPARdelta (NR1C2), PPARgamma (NR1C3)
Application: Functional activity screening
Reactivity: Human
1,539.00€ *
Review
MR (human) Reporter Assay Kit
MR (human) Reporter Assay Kit

Item number: IB-IB00502

This nuclear receptor assay system utilizes proprietary non-human cells engineered to provide constitutive high-level expression of full-length, unmodified human mineralocorticoid receptor (NR3C2), a ligand-dependent transcription factor commonly referred to as MR. INDIGO's reporter cells include the luciferase...
Keywords: MR, MCR, NR3C2, Mineralocorticoid receptor, Nuclear receptor subfamily 3 group C member 2
Application: Functional activity screening
Reactivity: Human
3,065.00€ *
Review
FXR (human) Reporter Assay Kit
FXR (human) Reporter Assay Kit

Item number: IB-IB00602

This nuclear receptor assay system utilizes proprietary non-human mammalian cells engineered to provide constitutive, high-level expression of human farnesoid X receptor (NR1H4), a ligand-dependent transcription factor commonly referred to as FXR. INDIGO's reporter cells include the luciferase reporter gene...
Keywords: BAR, NR1H4, Bile acid receptor, Farnesol receptor HRR-1, RXR-interacting protein 14, Farnesoid X-activated receptor,...
Application: Functional activity screening
Reactivity: Human
3,065.00€ *
Review
PR (human) Reporter Assay Kit
PR (human) Reporter Assay Kit

Item number: IB-IB05002

This nuclear receptor assay system utilizes proprietary human cells engineered to provide constitutive, high-level expression of the full-length human progesterone receptor (NR3C3), a ligand-dependent transcription factor commonly referred to as PR. INDIGO's reporter cells include the luciferase reporter gene...
Keywords: PR, PGR, NR3C3, Progesterone receptor, Nuclear receptor subfamily 3 group C member 3
Application: Functional activity screening
Reactivity: Human
3,065.00€ *
Review
ERbeta (human) Reporter Assay Kit
ERbeta (human) Reporter Assay Kit

Item number: IB-IB00411

This nuclear receptor assay system utilizes proprietary non-human cells engineered to provide constitutive, high-level expression of the full-length human estrogen receptor 2 (NR3A2), a ligand-dependent transcription factor commonly referred to as ERbeta. INDIGO's reporter cells include the luciferase reporter gene...
Keywords: ESR2, ESTRB, ER-beta, Estrogen receptor beta, Nuclear receptor subfamily 3 group A member 2
Application: Functional activity screening
Reactivity: Human
From 1,161.00€ *
Review
AhR (human) Assay Kit
AhR (human) Assay Kit

Item number: IB-IB06001

INDIGO's Aryl Hydrocarbon Receptor (AhR) Reporter Cells include the luciferase reporter gene functionally linked to an AhR-responsive promoter. Thus, quantifying changes in luciferase expression in the treated reporter cells provides a sensitive surrogate measure of the changes in AhR activity. The principle...
Keywords: Aryl Hydrocarbon Receptor (human) Assay Kit, AHR, AhR, BHLHE76, bHLHe76, Ah receptor, Aryl hydrocarbon receptor, Class E...
Application: Functional activity screening
From 1,161.00€ *
Review
PPARdelta (human) Reporter Assay Kit
PPARdelta (human) Reporter Assay Kit

Item number: IB-IB00121

This nuclear receptor assay system utilizes proprietary non-human cells engineered to provide constitutive, high-level expression of the human peroxisome proliferator-activated receptor delta (NR1C2), a ligand-dependent transcription factor commonly referred to as PPARD or PPARdelta. INDIGO's reporter cells include...
Keywords: NUCI, NUC1, NR1C2, PPARD, PPAR-beta, PPAR-delta, Nuclear hormone receptor 1, Nuclear receptor subfamily 1 group C member...
Application: Functional activity screening
Reactivity: Human
From 1,161.00€ *
Review
GR (human) Reporter Assay Kit
GR (human) Reporter Assay Kit

Item number: IB-IB00202

This nuclear receptor assay system utilizes proprietary non-human cells engineered to provide constitutive high-level expression of full-length, unmodified human glucocorticoid receptor (NR3C1), a ligand-dependent transcription factor, commonly referred to as GR. INDIGO's reporter cells include the luciferase...
Keywords: GR, GRL, NR3C1, Glucocorticoid receptor, Nuclear receptor subfamily 3 group C member 1
Application: Functional activity screening
Reactivity: Human
3,065.00€ *
Review
2 from 10 pages