Products from Indigo Biosciences

Indigo

Indigo Biosciences, Inc. was founded in 2005 in State College, Pennsylvania by Dr. Jack Vanden Heuvel and Dr. Blake Peterson. It remains a privately held biosciences company offering products and services focused on in vitro toxicology and nuclear receptors. These receptors comprise a major class of therapeutic drug targets. The company’s founders leveraged their collective expertise in nuclear receptor biology, toxicology, medical chemistry and molecular biology to establish the core platform technology of the company.

More information at: www.indigobiosciences.com

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NF-kappaB (Human) Reporter Assay System
NF-kappaB (Human) Reporter Assay System

Item number: IB-IB09001-32

Application: Functional activity screening
Species reactivity: human
From 1,448.00€ *
Review
AhR (human) Assay Kit
AhR (human) Assay Kit

Item number: IB-IB06001

INDIGO's Aryl Hydrocarbon Receptor (AhR) Reporter Cells include the luciferase reporter gene functionally linked to an AhR-responsive promoter. Thus, quantifying changes in luciferase expression in the treated reporter cells provides a sensitive surrogate measure of the changes in AhR activity. The principle...
Keywords: Aryl Hydrocarbon Receptor (human) Assay Kit, AHR, AhR, BHLHE76, bHLHe76, Ah receptor, Aryl hydrocarbon receptor, Class E...
Application: Functional activity screening
From 1,448.00€ *
Review
LXRb Reporter Assay System (dog)
LXRb Reporter Assay System (dog)

Item number: IB-D00301

Keywords: Nuclear receptor subfamily 1 group H member 2
Application: Functional activity screening
Species reactivity: dog
1,448.00€ *
Review
LXRa Reporter Assay System (dog)
LXRa Reporter Assay System (dog)

Item number: IB-D00311

Keywords: Nuclear receptor subfamily 1 group H member 3
Application: Functional activity screening
Species reactivity: dog
1,448.00€ *
Review
INSRb Reporter Assay System (human)
INSRb Reporter Assay System (human)

Item number: IB-IB28001

Protein function: Receptor tyrosine kinase which mediates the pleiotropic actions of insulin. Binding of insulin leads to phosphorylation of several intracellular substrates, including, insulin receptor substrates (IRS1, 2, 3, 4), SHC, GAB1, CBL and other signaling intermediates. Each of these phosphorylated...
Keywords: INSR, EC=2.7.10.1
Application: Functional activity screening
Species reactivity: human
1,448.00€ *
Review
INSRb Reporter Assay System (human)
INSRb Reporter Assay System (human)

Item number: IB-IB28002

Protein function: Receptor tyrosine kinase which mediates the pleiotropic actions of insulin. Binding of insulin leads to phosphorylation of several intracellular substrates, including, insulin receptor substrates (IRS1, 2, 3, 4), SHC, GAB1, CBL and other signaling intermediates. Each of these phosphorylated...
Keywords: INSR, EC=2.7.10.1
Application: Functional activity screening
Species reactivity: human
3,802.00€ *
Review
IGF-1R Reporter Assay System (human)
IGF-1R Reporter Assay System (human)

Item number: IB-IB29001

Protein function: Receptor tyrosine kinase which mediates actions of insulin- like growth factor 1 (IGF1). Binds IGF1 with high affinity and IGF2 and insulin (INS) with a lower affinity. The activated IGF1R is involved in cell growth and survival control. IGF1R is crucial for tumor transformation and survival of...
Keywords: IGF1R, EC=2.7.10.1
Application: Functional activity screening
Species reactivity: human
1,448.00€ *
Review
IGF-1R Reporter Assay System (human)
IGF-1R Reporter Assay System (human)

Item number: IB-IB29002

Protein function: Receptor tyrosine kinase which mediates actions of insulin- like growth factor 1 (IGF1). Binds IGF1 with high affinity and IGF2 and insulin (INS) with a lower affinity. The activated IGF1R is involved in cell growth and survival control. IGF1R is crucial for tumor transformation and survival of...
Keywords: IGF1R, EC=2.7.10.1
Application: Functional activity screening
Species reactivity: human
3,802.00€ *
Review
ADRA1A Reporter Assay System (human)
ADRA1A Reporter Assay System (human)

Item number: IB-IB31001

This is an all-inclusive cell-based luciferase reporter assay kit targeting the the Human Adrenoreceptor Alpha 1A (ADRA1A). INDIGO's ADRA1A reporter assay utilizes proprietary mammalian cells that have been engineered to provide constitutive expression of the ADRA1A. In addition to ADRA1A Reporter Cells, this kit...
Keywords: ADRA1A, ADRA1C, Alpha-1A adrenoceptor, Alpha-1A adrenoreceptor, Alpha-1A adrenergic receptor, Alpha-adrenergic receptor...
Application: Functional activity screening
Species reactivity: human
1,448.00€ *
Review
ADRA1A Reporter Assay System (human)
ADRA1A Reporter Assay System (human)

Item number: IB-IB31002

This is an all-inclusive cell-based luciferase reporter assay kit targeting the the Human Adrenoreceptor Alpha 1A (ADRA1A). INDIGO's ADRA1A reporter assay utilizes proprietary mammalian cells that have been engineered to provide constitutive expression of the ADRA1A. In addition to ADRA1A Reporter Cells, this kit...
Keywords: ADRA1A, ADRA1C, Alpha-1A adrenoceptor, Alpha-1A adrenoreceptor, Alpha-1A adrenergic receptor, Alpha-adrenergic receptor...
Application: Functional activity screening
Species reactivity: human
3,803.00€ *
Review
Human M-CSFR Reporter Assay System
Human M-CSFR Reporter Assay System

Item number: IB-IB30201

Protein function: Tyrosine-protein kinase that acts as cell-surface receptor for CSF1 and IL34 and plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of...
Keywords: Anti-FMS, Anti-CSF1R, Anti-CD115, Anti-CSF-1R, Anti-CSF-1-R, Anti-M-CSF-R, EC=2.7.10.1, Anti-CSF-1 receptor,...
Application: Functional activity screening
Species reactivity: human
1,448.00€ *
Review
Human M-CSFR Reporter Assay System
Human M-CSFR Reporter Assay System

Item number: IB-IB30202

Protein function: Tyrosine-protein kinase that acts as cell-surface receptor for CSF1 and IL34 and plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of...
Keywords: Anti-FMS, Anti-CSF1R, Anti-CD115, Anti-CSF-1R, Anti-CSF-1-R, Anti-M-CSF-R, EC=2.7.10.1, Anti-CSF-1 receptor,...
Application: Functional activity screening
Species reactivity: human
3,802.00€ *
Review
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