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Zu "K18026" wurden 28 Artikel gefunden!
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Artikelnummer: Cay40169-1
ABBV-CLS-484 is a dual inhibitor of protein tyrosine phosphatase 1N (PTP1N) and PTP2N (IC50s = 2.5 and 1.8 nM, respectively). It is selective for PTP1N and PTP2N over PTP6N and PTP11N (IC50s = >10 µM for both) but does inhibit PTP9N (IC50 = 15 nM). ABBV-CLS-484 (1 µM) potentiates IFN-gamma-induced decreases in the...
Schlagworte: | Osunprotafib,... |
Anwendung: | Dual PTPN1/PTPN2 inhibitor |
MW: | 385.5 D |
ab 669,00 €
Artikelnummer: MM-0019-P
Protein function: Non-receptor type tyrosine-specific phosphatase that dephosphorylates receptor protein tyrosine kinases including INSR, EGFR, CSF1R, PDGFR. Also dephosphorylates non-receptor protein tyrosine kinases like JAK1, JAK2, JAK3, Src family kinases, STAT1, STAT3, STAT5A, STAT5B and STAT6 either in the...
Schlagworte: | Anti-Ptpt, Anti-MPTP, Anti-Ptpn2, EC=3.1.3.48, Anti-Protein-tyrosine phosphatase PTP-2, Anti-Tyrosine-protein phosphatase... |
Anwendung: | WB, IP |
Wirt: | Mouse |
Spezies-Reaktivität: | human, monkey, rat , mouse |
684,00 €
Artikelnummer: A305-184A
Protein function: Non-receptor type tyrosine-specific phosphatase that dephosphorylates receptor protein tyrosine kinases including INSR, EGFR, CSF1R, PDGFR. Also dephosphorylates non-receptor protein tyrosine kinases like JAK1, JAK2, JAK3, Src family kinases, STAT1, STAT3 and STAT6 either in the nucleus or the...
Schlagworte: | Anti-PTPT, Anti-TCPTP, Anti-PTPN2, EC=3.1.3.48, Anti-T-cell protein-tyrosine phosphatase, Anti-Tyrosine-protein... |
Anwendung: | WB, IP |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
ab 164,00 €
Artikelnummer: A305-185A
Protein function: Non-receptor type tyrosine-specific phosphatase that dephosphorylates receptor protein tyrosine kinases including INSR, EGFR, CSF1R, PDGFR. Also dephosphorylates non-receptor protein tyrosine kinases like JAK1, JAK2, JAK3, Src family kinases, STAT1, STAT3 and STAT6 either in the nucleus or the...
Schlagworte: | Anti-PTPT, Anti-TCPTP, Anti-PTPN2, EC=3.1.3.48, Anti-T-cell protein-tyrosine phosphatase, Anti-Tyrosine-protein... |
Anwendung: | WB, IP |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
ab 164,00 €
Artikelnummer: BPS-30013
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Schlagworte: | PTPT, TCPTP, PTPN2, EC=3.1.3.48, T-cell protein-tyrosine phosphatase, Tyrosine-protein phosphatase non-receptor type 2, |
Anwendung: | Enzyme kinetics, dephosphorylation, inhibitor screening |
MW: | 62.3 kD |
481,00 €
Artikelnummer: MM-0018-P
Protein function: Non-receptor type tyrosine-specific phosphatase that dephosphorylates receptor protein tyrosine kinases including INSR, EGFR, CSF1R, PDGFR. Also dephosphorylates non-receptor protein tyrosine kinases like JAK1, JAK2, JAK3, Src family kinases, STAT1, STAT3, STAT5A, STAT5B and STAT6 either in the...
Schlagworte: | Anti-Ptpt, Anti-MPTP, Anti-Ptpn2, EC=3.1.3.48, Anti-Protein-tyrosine phosphatase PTP-2, Anti-Tyrosine-protein phosphatase... |
Anwendung: | WB, IP |
Wirt: | Mouse |
Spezies-Reaktivität: | mouse |
684,00 €
Artikelnummer: NSJ-R31988
0.5mg/ml if reconstituted with 0.2ml sterile DI water. TCPTP is also called as PTPN2. The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. Members of the PTP family share a highly conserved catalytic motif, which is essential for the catalytic activity. PTPs are known to be...
Schlagworte: | Anti-PTPT, Anti-PTPN2, Anti-TCPTP, EC=3.1.3.48, Anti-T-cell protein-tyrosine phosphatase, Anti-Tyrosine-protein... |
Anwendung: | WB, IHC (paraffin) |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, rat |
755,00 €
Artikelnummer: E-AB-60454.120
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. Members of the PTP family share a highly conserved catalytic motif, which is essential for the catalytic activity. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell...
Schlagworte: | Anti-PTPT, Anti-TCPTP, Anti-PTPN2, EC=3.1.3.48, Anti-T-cell protein-tyrosine phosphatase, Anti-Tyrosine-protein... |
Anwendung: | WB, IHC, IF |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, rat |
ab 218,00 €
Artikelnummer: ARG59035.50
Protein function: Non-receptor type tyrosine-specific phosphatase that dephosphorylates receptor protein tyrosine kinases including INSR, EGFR, CSF1R, PDGFR. Also dephosphorylates non-receptor protein tyrosine kinases like JAK1, JAK2, JAK3, Src family kinases, STAT1, STAT3 and STAT6 either in the nucleus or the...
Schlagworte: | Anti-PTPT, Anti-PTPN2, Anti-TCPTP, EC=3.1.3.48, Anti-T-cell protein-tyrosine phosphatase, Anti-Tyrosine-protein... |
Anwendung: | IHC (paraffin), WB |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, rat |
520,00 €
Artikelnummer: G-CAB1808.100
Anwendung: | IF, IHC, WB |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, rat |
ab 352,00 €
Artikelnummer: ATA-HPA015004.100
Protein function: Non-receptor type tyrosine-specific phosphatase that dephosphorylates receptor protein tyrosine kinases including INSR, EGFR, CSF1R, PDGFR. Also dephosphorylates non-receptor protein tyrosine kinases like JAK1, JAK2, JAK3, Src family kinases, STAT1, STAT3 and STAT6 either in the nucleus or the...
Schlagworte: | Anti-PTPT, Anti-PTPN2, Anti-TCPTP, EC=3.1.3.48, Anti-T-cell protein-tyrosine phosphatase, Anti-Tyrosine-protein... |
Anwendung: | IHC, WB, ICC |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
421,00 €
Artikelnummer: ATA-HPA046176.100
Protein function: Non-receptor type tyrosine-specific phosphatase that dephosphorylates receptor protein tyrosine kinases including INSR, EGFR, CSF1R, PDGFR. Also dephosphorylates non-receptor protein tyrosine kinases like JAK1, JAK2, JAK3, Src family kinases, STAT1, STAT3 and STAT6 either in the nucleus or the...
Schlagworte: | Anti-PTPT, Anti-PTPN2, Anti-TCPTP, EC=3.1.3.48, Anti-T-cell protein-tyrosine phosphatase, Anti-Tyrosine-protein... |
Anwendung: | IHC, WB, ICC |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
ab 300,00 €