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TN-16
Artikelnummer: TGM-T7800-100mg
Description: TN-16 is a microtubule polymerization inhibitor (IC50 :0.4-1.7 µM). Target: Microtubule Associated. Smiles: C(NC1=CC=CC=C1)(C)=C2C(=O)C(CC3=CC=CC=C3)NC2=O. References: Nakamura M , Kanda S , Kawamura M , et al. Effects of low concentration of vinblastine on the anchorage-independent growth and in vitro...
| Anwendung: | Microtubule polymerization inhibitor |
| CAS | 33016-12-5 |
| MW: | 306.36 D |
ab 34,00 €
TN-16
Artikelnummer: Cay21222-10
TN-16 is an inhibitor of microtubule polymerization (IC50 = 0.4-1.7 µM). It blocks taxol-induced assembly of tubulin (IC50 = 6 µM) and blocks colchicine (Cay-9000760) binding to tubulin. Like colchicine, TN-16 inhibits alkylation of tubulin. TN-16 induces metaphase arrest in renal cell carcinoma cells. TN-16 can be...
| Schlagworte: | NSC 239274, 3-[1-(phenylamino)ethylidene]-5-(phenylmethyl)-2,4-pyrrolidinedione |
| Anwendung: | Microtubule polymerization inhibitor |
| CAS | 33016-12-5 |
| MW: | 306.4 D |
ab 61,00 €
