Zu "193746-75-7" wurden 3 Artikel gefunden!
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SB-242235
Artikelnummer: SYN-1076-M001
Soluble in DMSO. The p38 mitogen-activated protein kinase (MAPK) signaling pathway is activated by numerous inflammatory mediators and environmental stresses. SB-242235 is a potent and moderately selective p38 MAP kinase inhibitor that may be an effective therapy for cytokine-mediated diseases such as autoimmune or...
| Schlagworte: | SB-242235 |
| Anwendung: | p38 inhibitor |
| CAS | 193746-75-7 |
| MW: | 353,4 D |
ab 293,00 €
SB-242235
Artikelnummer: Cay35117-10
SB-242235 is an inhibitor of p38alpha MAPK (IC50 = 0.019 µM). It is selective for p38alpha MAPK over a panel of 10 kinases, including ERK2, JNK1, EGFR, and C-RAF (IC50s = >10 µM for all). SB-242235 inhibits IL-1alpha-induced production of nitric oxide (NO) in bovine articular cartilage explants but not...
| Schlagworte: | 4-[4-(4-fluorophenyl)-1-(4-piperidinyl)-1H-imidazol-5-yl]-2-methoxy-pyrimidine |
| Anwendung: | P38alpha MAPK inhibitor |
| CAS | 193746-75-7 |
| MW: | 353.4 D |
ab 114,00 €
SB 242235
Artikelnummer: TGM-T4078-100mg
Description: SB 242235 is a potent and selective p38 MAP kinase inhibitor that may be an effective therapy for cytokine-mediated diseases. Target: p38 MAPK, Autophagy. Smiles: COc1nccc(n1)-c1c(ncn1C1CCNCC1)-c1ccc(F)cc1. References: Badger, A.M., et al., Differential effects of SB 242235, a selective p38...
| Schlagworte: | SB-242235, SB242235 |
| Anwendung: | P38alpha MAPK inhibitor |
| CAS | 193746-75-7 |
| MW: | 353.39 D |
ab 39,00 €
