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2-cyano-Pyrimidine
2-cyano-Pyrimidine

Artikelnummer: Cay10007121-1

Cathepsin K is a lysosomal cysteine protease found in osteoclasts whose elevated activity has been linked to the formation of osteoporosis and arthritis. 2-cyano-Pyrimidine is a cathepsin K inhibitor whose basic structure and derivatives are being studied for the treatment of osteoporosis. 2-cyano-Pyrimidine has an...
Schlagworte: 2-pyrimidinecarbonitrile
Anwendung: Cathepsin K inhibitor
CAS 14080-23-0
MW: 105.1 D
ab 19,00 €
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2-Cyanopyrimidine
2-Cyanopyrimidine

Artikelnummer: TGM-T7451-1g

Description: 2-Cyanopyrimidine (m-Hydroxyphenylpropionic acid) is inhibitor of cathepsin K(IC50 : 170 nM). Target: Cysteine Protease. Smiles: N#CC1=NC=CC=N1. References: Rankovic Z , Cai J , Kerr J , et al. Optimisation of 2-cyano-pyrimidine inhibitors of cathepsin K: Improving selectivity over hERG[J]. Bioorganic...
Schlagworte: 2-cyano-Pyrimidine
Anwendung: Cathepsin K inhibitor
CAS 14080-23-0
MW: 105.1 D
29,00 €
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