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COVID-19 Forschung
COVID-19 IgM/IgG Rapid Test
COVID-19 IgM/IgG Rapid Test

Artikelnummer: E-UNCOV-40

COVID-19 (Corona Virus Disease) is an infectious disease caused by the most recently discovered coronavirus SARS-CoV-2. This highly contagious new virus and disease were unknown before the outbreak began in Wuhan, China which spread all over the world very quickly. COVID-19 IgG/IgM Rapid Test (Whole Blood/...
Schlagworte: SARS-CoV-2 antibody test
Anwendung: Lateral flow
Reaktivität: Human
245,00 €
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COVID-19 Forschung
Remdesivir
Remdesivir

Artikelnummer: Cay30354-5

Remdesivir is a prodrug form of the antiviral nucleoside analog GS-441524 (Cay-30469). Upon entry into cells, remdesivir is metabolized into the nucleotide triphosphate GS-441524. Remdesivir is active against Middle East respiratory syndrome coronavirus (MERS-CoV) and severe acute respiratory syndrome CoV (SARS-CoV)...
Schlagworte: GS-5734, N-[(S)-hydroxyphenoxyphosphinyl)-L-alanine, 2-ethylbutyl ester, 6-ester with...
Anwendung: GS-441524 prodrug, SARS type antiviral
CAS 1809249-37-3
MW: 602.6 D
ab 219,00 €
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COVID-19 Forschung
MK2206 (dihydrochloride)
MK2206 (dihydrochloride)

Artikelnummer: LKT-M4000.1

MK2206 is a Akt inhibitor, is also an orally bioavailable allosteric inhibitor of the serine/threonine protein kinase Akt (protein kinase B) with potential antineoplastic activity. Akt inhibitor MK2206 binds to and inhibits the activity of Akt in a non-ATP competitive manner, which may result in the inhibition of...
Schlagworte: MK-2206 . 2HCl, 8-(4-(1-aminocyclobutyl)phenyl)-9-phenyl-8,9-dihydro-[1,2,4]triazolo[3,4-f][1,6]naphthyridin-3(2H)-one...
Anwendung: AKT inhibitor
CAS 1032350-13-2
MW: 445.94 D
ab 60,00 €
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COVID-19 Forschung
MK-2206 (hydrochloride)
MK-2206 (hydrochloride)

Artikelnummer: Cay11593-1

Three related forms of the kinase Akt (1, 2, 3, also known as protein kinase B isoforms PKBalpha, beta, gamma) modulate cell proliferation, metabolism, and survival as well as angiogenesis. MK-2206 is an orally active, allosteric Akt inhibitor that is equally potent toward purified human recombinant Akt1 and Akt2...
Schlagworte: 8-[4-(1-aminocyclobutyl)phenyl]-9-phenyl-1,2,4-triazolo[3,4-f][1,6]naphthyridin-3(2H)-one, dihydrochloride
Anwendung: Allosteric Akt inhibitor
CAS 1032350-13-2
MW: 480.4 D
ab 43,00 €
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COVID-19 Forschung
Ruxolitinib
Ruxolitinib

Artikelnummer: AG-CR1-3624-M025

White to off-white solid. Soluble in DMSO or ethanol. Insoluble in water. Antineoplastic, anti-inflammatory and immunomodulating agent, Orally bioavailable potent ATP mimetic that inhibits both JAK1 and JAK2 with IC50 values of 2.7 and 4.5nM, respectively and is less selective for JAK3 (IC50 = 322nM), Affects DC...
Schlagworte: INCB018424, INC 424
Anwendung: JAK1 inhibitor, JAK2 inhibitor
CAS 941678-49-5
MW: 306,4 D
ab 72,00 €
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COVID-19 Forschung
Anti-ACE2 (human), mAb AC18F (ATTO488)
Anti-ACE2 (human), mAb AC18F (ATTO488)

Artikelnummer: AG-20A-0032-C050

Recognizes human ACE2. Liquid. 0.2µm-filtered solution in PBS, pH 7.4. Contains no preservatives. ACE2 has direct effects on cardiac functions. It is expressed predominantly in vascular endothelial cells of the heart and kidney. ACE2 converts angiotensin I to angiotensin 1-9. ACE2 was also identified as a functional...
Schlagworte: SARS Receptor, Angiotensin-converting Enzyme 2, ACEH
Anwendung: ELISA, FC, WB
Reaktivität: Human
ab 187,00 €
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COVID-19 Forschung
Chloroquine (phosphate)
Chloroquine (phosphate)

Artikelnummer: Cay14194-25

Chloroquine is an aminoquinoline antimalarial compound that acts by preventing detoxification of hematin within the Plasmodium digestive vacuole. Although it has lost its antimalarial efficacy through the development of mutations within the P. falciparum chloroquine resistance transporter, chloroquine is widely used...
Schlagworte: Aralen, DL-Chloroquine, NSC 14050, N4-(7-chloro-4-quinolinyl)-N1,N1-diethyl-1,4-pentanediamine, diphosphate
Anwendung: Autophagy inhibitor, Antimalarial
CAS 50-63-5
MW: 515.9 D
ab 59,00 €
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COVID-19 Forschung
Hydroxychloroquine (sulfate)
Hydroxychloroquine (sulfate)

Artikelnummer: Cay17911-50

Hydroxychloroquine (HCQ) is a synthetic quinine derivative commonly used as an antimalarial drug. It is also useful in managing systemic lupus erythematosus, rheumatoid arthritis, and other diseases. HCQ inhibits autophagy and induces autophagic cell death (IC50 = 30 µM), suggesting potential applications in...
Schlagworte: HCQ, NSC 4375, 2-[[4-[(7-chloro-4-quinolinyl)amino]pentyl]ethylamino]-ethanol, monosulfate
Anwendung: Antimalarial, Lupus erythematosus suppressant
CAS 747-36-4
MW: 434 D
ab 32,00 €
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COVID-19 Forschung
SARS-CoV-2 (2019-nCoV) Papain-Like Protease Protein , recombinant
SARS-CoV-2 (2019-nCoV) Papain-Like Protease Protein ,...

Artikelnummer: E-PKSR030472.50

GenBank: QHD43415.1. Nsp3 is responsible for the cleavages located at the N-terminus of the replicase polyprotein. In addition, PL-PRO possesses a deubiquitinating/deISGylating activity and processes both 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains from cellular substrates. Participates together with nsp4 in...
Schlagworte: Non-structural protein 3, nsp3, PL2-PROPapain-like proteinase, PL-PRO, SARS coronavirus main proteinase
Reaktivität: Sars-cov-2
MW: 34 kD
ab 243,00 €
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COVID-19 Forschung
GS-441524 (Remdesivir Metabolite)
GS-441524 (Remdesivir Metabolite)

Artikelnummer: AG-CR1-3722-M010

Soluble in DMSO (10mg/ml) or DMF (10mg/ml). GS-441524 is the active metabolite of the broad-spectrum antiviral Remdesivir. GS-441524 is an adenosine nucleotide analog in viral RNA production. It is a nucleotide analog inhibitor of RNA-dependent RNA polymerases (RdRps). The compound interferes with the action of...
Anwendung: Antiviral nucleoside analog, active remdesivir metabolite
CAS 1191237-69-0
MW: 291.3 D
ab 55,00 €
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COVID-19 Forschung
COVID-19 IgG/IgM Rapid Test Development Kit
COVID-19 IgG/IgM Rapid Test Development Kit

Artikelnummer: E-ELC-RTD001.500

Intended Use: This kit contains essential reagents for the development of COVID-19 IgG/IgM Lateral Flow (Rapid Test) assay to help with the qualitative detection of IgG and IgM antibodies specific to SARS-CoV-2 in human biological fluids. Kit Components & Storage: The components listed can be purchased...
Schlagworte: SARS-CoV-2 IgG/IgM Rapid Test Development Kit
Anwendung: Lateral Flow, SARS-CoV-2, COVID-19 IgG/IgM Rapid Test Development
Reaktivität: Sars-cov-2
ab 536,00 €
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COVID-19 Forschung
GS-441524
GS-441524

Artikelnummer: Cay30469-10

Anwendung: Antiviral nucleoside analog, Active remdesivir metabolite
CAS 1191237-69-0
ab 37,00 €
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