Nitrotyrosine ELISA Kit

Nitrotyrosine ELISA Kit
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
KOA0888 1 kit - -

6 - 10 Werktage*

877,00 €
 
This kit contains: 96 wells coated plate, Target Protein Standard, HRP Conjugated Monoclonal... mehr
Produktinformationen "Nitrotyrosine ELISA Kit"
This kit contains: 96 wells coated plate, Target Protein Standard, HRP Conjugated Monoclonal Antibody, Diluent, Wash buffer, TMB Substrate and stop reagent, see protocol for additional information. Nitrotyrosine has been identified as a marker of inflammation and NO production. Nitrotyrosine is formed in presence of the active metabolite NO. Various pathways including the formation of peroxinitrite lead to nitrotyrosine production. Since nitrotyrosine is a stable end product of peroxynitrite oxidation, assessment of its plasma concentration may be useful as a marker of NO-dependent damage in vivo. Since NOX is only an indicator for enhanced NO production, protein associated nitrotyrosine might be a more suitable marker for damage induced by reactive nitrogen intermediates derived from NO. Furthermore, most proteins have a longer half life in the circulation than NOX levels. The presence of nitrotyrosine has been detected in various inflammatory processes including atherosclerotic plaques, celiac disease, rheumatoid arthritis, chronic renal failure and septic shock. In normal plasma low, undetectable, levels of nitrotyrosine are present. Nitrosylation of the amino acid tyrosine occurs both for free tyrosine and for protein bound tyrosine.
Hersteller: Rockland Immunochemicals
Hersteller-Nr: KOA0888

Eigenschaften

Anwendung: ELISA
Antikörper-Typ: Monoclonal

Datenbank Information

Handhabung & Sicherheit

Lagerung: +4°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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