Stem Cell Factor

Stem Cell Factor
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
009-001-W20-0010 10 µg - -

6 - 10 Werktage*

420,00 €
 
Stem Cell Factor purity was determined to be greater than 98% as determined by analysis by... mehr
Produktinformationen "Stem Cell Factor"
Stem Cell Factor purity was determined to be greater than 98% as determined by analysis by UV-Spectroscopy at 280nm and by reducing and non-reducing SDS-pAGE. Protein function: Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. KITLG/SCF binding can activate several signaling pathways. Promotes phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, and subsequent activation of the kinase AKT1. KITLG/SCF and KIT also transmit signals via GRB2 and activation of RAS, RAF1 and the MAP kinases MAPK1/ERK2 and/or MAPK3/ERK1. KITLG/SCF and KIT promote activation of STAT family members STAT1, STAT3 and STAT5. KITLG/SCF and KIT promote activation of PLCG1, leading to the production of the cellular signaling molecules diacylglycerol and inositol 1,4,5- trisphosphate. KITLG/SCF acts synergistically with other cytokines, probably interleukins. [The UniProt Consortium]
Schlagworte: MGF, KITLG
Hersteller: Rockland Immunochemicals
Hersteller-Nr: 009-001-W20-0010

Eigenschaften

Anwendung: Cell culture
Konjugat: No
Wirt: E.coli
Spezies-Reaktivität: human

Handhabung & Sicherheit

Lagerung: +4°C
Versand: +20°C (International: +20°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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