RLN2, Recombinant, Human, aa25-185, His-Tag (Prorelaxin H2 Isoform 1, H2, H2-RLX, RLXH2)

RLN2, as known as prorelaxin H2 isoform 1, belongs to the insulin gene superfamily. This family is produced by the ovary, and targets the mammalian reproductive system to ripen the cervix, elongate the pubic symphysis and inhibit uterine contraction. It may have additional roles in enhancing sperm motility, regulating blood pressure, controlling heart rate and releasing oxytocin and vasopressin. It is 18kD in size and 185aa in length. It contains a 24aa signal sequence, a 3.3kD, 29aa B domain, a 106aa C (or connecting) domain, and a C-terminal, 2.7kD, 24aa A domain. Source: Recombinant protein corresponding to aa25-185 from human RLN2, fused to His-Tag at C-terminal, expressed in insect cell. Molecular Weight: ~19.3kD (170aa) 18-28kD (SDS-PAGE under reducing conditions.), Endotoxin: <1EU/1ug (determined by LAL method), AA Sequence: ADPDSWMEEV IKLCGRELVR AQIAICGMST WSKRSLSQED APQTPRPVAE IVPSFINKDT ETINMMSEFV ANLPQELKLT LSEMQPALPQ LQQHVPVLKD SSLLFEEFKK LIRNRQSEAA DSSPSELKYL GLDTHSRKKR QLYSALANKC CHVGCTKRSL ARFCHHHHHH, Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.