Recombinant Human Flap Endonuclease 1/FEN1 Protein (RPES4182)

Recombinant Human Flap Endonuclease 1/FEN1 Protein (RPES4182)
NEU
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
G-RPES4182.10 10 µg - - -

9 - 20 Werktage*

318,00 €
 
Recombinant Human Flap Endonuclease 1/FEN1 Protein from Assay Genie. Recombinant Human Flap... mehr
Produktinformationen "Recombinant Human Flap Endonuclease 1/FEN1 Protein (RPES4182)"
Recombinant Human Flap Endonuclease 1/FEN1 Protein from Assay Genie. Recombinant Human Flap Endonuclease 1/FEN1 Protein is a highly purified recombinant protein produced in E.coli and for the use in functional assays from Assay Genie.. Protein function: Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as a genome stabilization factor that prevents flaps from equilibrating into structurs that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA, and exhibits RNase H activity. Also involved in replication and repair of rDNA and in repairing mitochondrial DNA. [The UniProt Consortium]
Schlagworte: MF1, RAD2, FEN-1, hFEN-1, DNase IV, Flap endonuclease 1, Maturation factor 1, Flap structure-specific endonuclease 1
Hersteller: Assay Genie
Hersteller-Nr: RPES4182

Eigenschaften

Konjugat: No
Exprimiert in: E.coli
Ursprungsart: Human
Format: Highly Purified

Datenbank Information

KEGG ID : K04799 | Passende Produkte
UniProt ID : P39748 | Passende Produkte

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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