Progranulin (human) (rec.) (untagged)

Progranulin (human) (rec.) (untagged)
%
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Rabatt Preis
AG-40A-0188Y-C010 10 µg -

3 - 9 Werktage*

10 %
215,00 €
193,50 €
AG-40A-0188Y-C050 50 µg -

3 - 9 Werktage*

10 %
517,00 €
465,30 €
 
Signal peptide and human progranulin (aa 1-593) is untagged. Reflects the native sequence with no... mehr
Produktinformationen "Progranulin (human) (rec.) (untagged)"
Signal peptide and human progranulin (aa 1-593) is untagged. Reflects the native sequence with no additional aa. Activates phospho-ERK1/2 in neuronal mouse P19 cells. Regulates food intake and body weight. Progranulin (PGRN) is a widely expressed pluripotent growth factor which plays a role in processes such as development, wound repair and inflammation by activating signaling cascades that control cell cycle progression and cell motility. Its function in the central nervous system is of interest, as mutations in the PGRN gene were found in cases of frontotemporal degeneration (FTLD). In addition, PGRN has also been linked to tumorigenesis. Progranulin is a biomarker for FTLD, other types of Alzheimer's Disease (AD) and potentially for MCI (Mild Cognitive Impairment). Additionally, PGRN is described as a new ligand of TNF receptors and a potential therapeutic against inflammatory disease like arthritis.
Schlagworte: GRN, Proepithelin, PEPI, PC Cell-derived Growth Factor
Hersteller: AdipoGen Life Sciences
Hersteller-Nr: AG-40A-0188Y

Eigenschaften

Anwendung: Cell culture
Konjugat: No
Wirt: Human cells
Spezies-Reaktivität: human
MW: 74 kD
Reinheit: >98%
Format: Lyophilized

Datenbank Information

UniProt ID : P28799 | Passende Produkte
Gene ID GeneID 2896 | Passende Produkte

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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