Nampt (Visfatin/PBEF) (human, rec.) (His) (BULK)

Nampt (Visfatin/PBEF) (human, rec.) (His) (BULK)
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
AG-40A-0018AA-C500 500 µg -

3 - 9 Werktage*

2.585,00 €
 
Intracellular human Nampt (visfatin/PBEF) (amino acids 1-491) is fused at the C-terminus to a... mehr
Produktinformationen "Nampt (Visfatin/PBEF) (human, rec.) (His) (BULK)"
Intracellular human Nampt (visfatin/PBEF) (amino acids 1-491) is fused at the C-terminus to a His-tag. Shows adipogenic effects in stimulated differentiating 3T3-L1 cells. Lyophilized. Salt-free. Nicotinamide phosphoribosyltransferase (Nampt, pre-B cell colony-enhancing factor, PBEF, Visfatin) is an 52kDa adipokine secreted by adipose tissue and involved in the biosynthesis of nicotinamide adenine dinucleotide (NAD). Two forms of Nampt exist, an intracellular form (iNampt) and an extracellular form (eNampt). While the function of iNampt as an essential and rate-limiting NAD biosynthetic enzyme is well established, the physiological role of eNampt is still a matter of debate. Nampt has various functions, including the promotion of vascular smooth muscle cell maturation and inhibition of neutrophil apoptosis. It activates insulin receptor and has insulin-mimetic effects, lowering blood glucose and improving insulin sensitivity. The protein is highly expressed in visceral fat and serum levels of the protein correlate with obesity.
Schlagworte: Pre-B Cell Colony Enhancing Factor 1, PBEF1, Nicotinamide Phosphoribosyltransferase
Hersteller: AdipoGen Life Sciences
Hersteller-Nr: AG-40A-0018AA

Eigenschaften

Anwendung: Bioassays
Konjugat: No
Exprimiert in: E.coli
Ursprungsart: Human
MW: 52 kD
Format: Lyophilized

Datenbank Information

KEGG ID : K03462 | Finde Alternativen
UniProt ID : P43490 | Finde Alternativen

Handhabung & Sicherheit

Lagerung: -20°C
Versand: -20°C (International: -20°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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