Myostatin, active, His Tag, human recombinant (rHuMyostatin-His), plant based, bio-clean

Myostatin, active, His Tag, human recombinant (rHuMyostatin-His), plant based, bio-clean
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
99863.5 5 µg - -

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123,00 €
 
Recombinant human Myostatin contains a 6-His-tag at the N-terminal end, is produced by transient... mehr
Produktinformationen "Myostatin, active, His Tag, human recombinant (rHuMyostatin-His), plant based, bio-clean"

Recombinant human Myostatin contains a 6-His-tag at the N-terminal end, is produced by transient expression in non-transgenic plants and is purified by sequential chromatography (FPLC). This product contains no animalderived components or impurities. The biological activity of Myostatin is measured by its ability to inhibit mouse plasmacytoma cell line (MPC-11) cells. Myostatin (GDF8, MSTN) belongs to the transforming growth factor beta (TGFBs) superfamily, which includes : TGF betas, the bone morphogenetic protein (BMPs), growth differentiation factors (GDFs), activins and inhibins. As other members of this superfamily, is synthesized and secreted as a homodimeric prepropeptide that is cleaved by proprotein convertases such as furin to generate the dimeric N- terminal propeptide and the dimeric C-terminal mature active protein.Myostatin is one of the most important protein that controls myoblast proliferation and it is a potent negative regulator of skeletal muscle mass in a number of animal species. Several studies have shown that Myostatin could play an important role in cardiac development and physiology.Genetic deletion of Myostatin or in vivo administration of the Myostatin propeptide induces muscle hypertrophy as well as enhanced glucose utilization and insulin sensitivity and a reduction in overall fat mass.

Schlagworte: GDF8, MSTN, GDF-8, Myostatin, Growth/differentiation factor 8
Hersteller: Biomol GmbH
Hersteller-Nr: 99863.5

Eigenschaften

Anwendung: Cell culture, WB
Konjugat: No
Exprimiert in: Nicotiana
Ursprungsart: Human
MW: 24,8 kD
Reinheit: >97%
Format: Lyophilized

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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