MIF (human recombinant)

MIF (human recombinant)
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
Cay14493-100 100 µg -

6 - 10 Werktage*

595,00 €
 
Macrophage Migration Inhibitory Factor (MIF) is a small, pro-inflammatory cytokine. MIF signaling... mehr
Produktinformationen "MIF (human recombinant)"
Macrophage Migration Inhibitory Factor (MIF) is a small, pro-inflammatory cytokine. MIF signaling is important in septic shock, arthritis, colitis, and cardiovascular diseases. MIF counteracts glucocorticoid signaling, which would otherwise inhibit inflammation. Secreted MIF binds to CD74 receptors, which then couple to CD44, during monocyte recruitment. In addition to CD44 binding, MIF is an enzymatically active keto-enol tautomerase that is inhibited by isothiocyanates such as sulforaphane. Overexpression of MIF has been seen in several cancers. MIF overexpression has been shown to promote hypoxia induced HIF-1alpha stabilization leading to changes in the tumor microenvironment, including stimulation of angiogenesis and neovascularization.Synonyms: Macrophage Migration Inhibitory Factor. Purity: >95% estimated by SDS-PAGE. Source: Recombinant human MIF expressed in E. coli. MW: 12.6 kDa. UniProt Accession #: P14174.
Schlagworte: MIF, MIF, GIF, MIF, GIF, GLIF, L-dopachrome isomerase, L-dopachrome isomerase, L-dopachrome tautomerase, L-dopachrome tautomerase, Phenylpyruvate tautomerase, Phenylpyruvate tautomerase, Glycosylation-inhibiting factor, Glycosylation-inhibiting factor, Ma
Hersteller: Cayman Chemical
Hersteller-Nr: 14493

Eigenschaften

Anwendung: Enzyme activity, WB
Konjugat: No
Reinheit: >95% estimated by SDS-PAGE
Format: Purified

Handhabung & Sicherheit

Lagerung: -80°C
Versand: -80°C (International: -80°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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