Macrophage Inflammatory protein-4 (CCL18), His Tag, human recombinant (rHuMIP-4-His)

Recombinant human MIP-4, fused with a 25 amino acid His tag at N-terminus, produced in E.coli is a single, non-glycosylated, polypeptide chain containing 93 amino acids (22-89) and having a molecular mass of 10.4kDa. Chemokine (C-C motif) ligand 18 (CCL18) is a small cytokine belonging to the CC chemokine family that was previously called PARC (pulmonary and activation-regulated chemokine). CCL18 is approximately 60% identical in amino acid sequence to CCL3. It is expressed at high levels in lung and at lower levels in certain lymphoid tissues, such as the lymph nodes, and is chemotactic for activated T cells and non activated lymphocytes. The gene for human CCL18 contains three exons and is located on chromosome 17.