Macrophage Colony Stimulating Factor, human recombinant (rHuM-CSF)

Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. CSF-1 induces cells of the monocyte/macrophage lineage. It plays a role in immunological defenses, bone metabolism, lipoproteins clearance, fertility and pregnancy. (www.uniprot.org) Produced in baculovirus as a disulfide linked homodimer, glycosylated, polypeptide chain containing 2 x 149 amino acids.