Interleukin-3, active His Tag, human recombinant (rHuIL-3-His), plant based, bio-clean

Interleukin-3, active His Tag, human recombinant (rHuIL-3-His), plant based, bio-clean
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
99868.10 10 µg - -

Fragen Sie uns nach der Lieferzeit

229,00 €
99868.20 20 µg - -

Fragen Sie uns nach der Lieferzeit

370,00 €
99868.100 100 µg - -

Fragen Sie uns nach der Lieferzeit

1.087,00 €
 
Recombinant human Interleukin-3 contains a 8-His-tag at the N-terminal end, is produced by... mehr
Produktinformationen "Interleukin-3, active His Tag, human recombinant (rHuIL-3-His), plant based, bio-clean"

Recombinant human Interleukin-3 contains a 8-His-tag at the N-terminal end, is produced by transient expression in non-transgenic plants and is purified by sequential chromatography (FPLC). This product contains no animal-derived components or impurities. The activity is determined by the dose-dependent stimulation of TF-1 cells. IL-3 is a potent growth factor involved in a variety of cell activities such as cell growth, differentiation and apoptosis. It takes part of several biological responses such as proliferation, and differentiation of a broad range of hematopoietic progenitor cells into erythrocytes, granulocytes, monocytes, megakaryocytic and mast cells. IL3 also induces the production of several enzymes involved in cellular metabolism, differentiation, and DNA/RNA metabolism.IL-3 is produced by activated T-lymphocytes, keratinocytes, NK-cells, mast cells, endothelial cells and monocytes. The biological activity of IL-3 is mediated through specific cell surface receptor that is composed of alpha and beta subunits. Alpha subunit is responsible for the binding and beta subunit transmits signals across the plasma membrane, il-3 is known to activate three signalling pathways: JAK/STAT, RAS/RAF/MAP kinase, and the PI-3kinase/PKB pathways.IL-3 is also implicated in the pathogenesis of several diseases. Recombinant protein has been widely used in clinical practice.

Schlagworte: IL3, MCGF, IL-3, Interleukin-3, Mast cell growth factor, P-cell-stimulating factor, Hematopoietic growth factor, Multipotential colony-stimulating factor
Hersteller: Biomol GmbH
Hersteller-Nr: 99868.10

Eigenschaften

Anwendung: Cell culture, WB
Konjugat: No
Exprimiert in: Nicotiana
Ursprungsart: Human
Reinheit: >97%
Format: Lyophilized

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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