Interleukin-25/IL-25 Protein(C-6His) (recombinant human)

Interleukin-25/IL-25 Protein(C-6His) (recombinant human)
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
E-PKSH032634.10 10 µg -

7 - 16 Werktage*

152,00 €
E-PKSH032634.50 50 µg -

7 - 16 Werktage*

446,00 €
 
Protein Construction: Recombinant Human Interleukin-25 is produced by our Mammalian expression... mehr
Produktinformationen "Interleukin-25/IL-25 Protein(C-6His) (recombinant human)"
Protein Construction: Recombinant Human Interleukin-25 is produced by our Mammalian expression system and the target gene encoding Tyr33-Gly177 is expressed with a 6His tag at the C-terminus. Sequence: Tyr33-Gly177. Fusion tag: C-6His Endotoxin: < 1.0 EU per µg as determined by the LAL method. Apparent Molecular Mass: 20-26 kDa. Protein function: Interleukin 25 (IL-25) belongs to the Interleukin 17 (IL-17) family of proteins, which is comprised of six members (IL-17, IL-17B through IL-17F). These proteins are secreted and are structurally related by sharing a conserved cysteine-knot fold near the C-terminus, but have considerable sequence divergence at the N-terminus. With the exception of IL-17B, which exists as a non-covalently linked dimer, all IL-17 family members are disulfide-linked dimers. IL-17 family proteins are pro-inflammatory cytokines that induce local cytokine production and are involved in the regulation of immune functions. Human interleukin-17E (IL17E), also referred to as Interleukin-25 (IL25), is a distinct member of the IL17 cytokine family comprised of at least six members sharing a conserved cysteine-knot structure but divergent at the N-terminus. IL25 is a glycoprotein secreted as dimers by innate effector eosinophils and basophils, and present at very low levels in various peripheral tissues. IL25, together with IL17B, are li Protein function: Induces activation of NF-kappa-B and stimulates production of the proinflammatory chemokine IL-8. Proinflammatory cytokine favoring Th2-type immune responses. [The UniProt Consortium]
Schlagworte: IL25, IL-25, IL17E, IL-17E, Interleukin-25, Interleukin-17E, Recombinant Human Interleukin-25/IL-25 Protein(C-6His)
Hersteller: Elabscience
Hersteller-Nr: E-PKSH032634

Eigenschaften

Konjugat: No
Wirt: Human cells
Spezies-Reaktivität: human
MW: 16.7 kD
Format: Lyophilized

Handhabung & Sicherheit

Lagerung: -80°C
Versand: +4°C (International: +20°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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