
Artikelnummer | Größe | Datenblatt | Manual | SDB | Lieferzeit | Menge | Preis |
---|---|---|---|---|---|---|---|
97502.2 | 2 µg | - | - | 3 - 10 Werktage* | 70,00 € | ||
97502.10 | 10 µg | - | - | 3 - 10 Werktage* | 180,00 € | ||
97502.100 | 100 µg | - | - | 3 - 10 Werktage* | - |
Größere Menge gewünscht? Bulk-Anfrage
Human recombinant IL-23 produced in HEK cells is a glycosylated disulfide linked homodimer, having a total molecular weight of 43kDa and 19kDa heterodimer. IL23 is composed of a subunit of the heterodimeric cytokine IL23 and the p40 subunit of interleukin 12 (IL12B). Interleukin-23 (IL-23) belongs to the IL-12 family and is produced by antigen presenting cells. IL-23 using IL12RB1 and IL-23R (specific for IL-23) can activate STAT and NF-kappaB pathways and stimulate the production of interferon-gamma.). IL-23 is known to take a vital part in the inflammation process and is associated with auto immune diseases. However, unlike IL12, which acts primarily on naive CD4(+) T cells, IL23 preferentially acts on memory CD4(+) T cells.
Schlagworte: | Interleukin 23 alpha subunit p19, Interleukin-12 subunit beta p40, SGRF, IL23P19, IL-23-A, interleukin-six, G-CSF related factor, JKA3 induced upon T-cell activation, interleukin 12B (natural killer cell stimulatory factor 2 cytotoxic lymphocyte maturatio |
Hersteller: | Biomol GmbH |
Hersteller-Nr: | 97502 |
Eigenschaften
Anwendung: | Cell Culture |
Konjugat: | No |
Exprimiert in: | Human cells |
Ursprungsart: | Human |
Reinheit: | >95% |
Format: | Lyophilized |
Datenbank Information
KEGG ID : | K05426 | Finde Alternativen |
UniProt ID : | Q9NPF7 | Finde Alternativen |
Gene ID | GeneID 51561 | Finde Alternativen |
Handhabung & Sicherheit
Lagerung: | -20°C |
Versand: | +20°C (International: +20°C) |
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!