Interleukin-1ß/IL-1ß Protein (recombinant human)

Interleukin-1ß/IL-1ß Protein (recombinant human)
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
E-PKSH032628.10 10 µg - -

7 - 16 Werktage*

141,00 €
E-PKSH032628.50 50 µg - -

7 - 16 Werktage*

410,00 €
 
Activity: Measured by its ability to induce NFKB reporter gene expression in HEK 293 cell... mehr
Produktinformationen "Interleukin-1ß/IL-1ß Protein (recombinant human)"
Activity: Measured by its ability to induce NFKB reporter gene expression in HEK 293 cell line.The ED50 for this effect is typically 142 pg/mL Protein Construction: Recombinant Human Interleukin-1 beta is produced by our E.coli expression system and the target gene encoding Ala117-Ser269 is expressed. Sequence: Ala117-Ser269. Endotoxin: < 1.0 EU per µg as determined by the LAL method. Apparent Molecular Mass: 17 kDa. Protein function: IL1B belongs to the IL-1 family. Interleukin 1 (IL-1) is a family of polypeptide cytokines consisting of two agonists, IL-1 alpha (IL-1F1) and IL-1 beta (IL-1F2) encoded by two distinct genes and perform identical biological functions. IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response. It is identified as endogenous pyrogens, and is reported to stimulate the release of prostaglandin and collagenase from synovial cells. Protein function: Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B-cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T-helper 1 (Th1) cells (PubMed:10653850). [The UniProt Consortium]
Schlagworte: IL1F2, IL-1 beta, Catabolin, Interleukin-1 beta, Recombinant Human Interleukin-1ß/IL-1ß Protein
Hersteller: Elabscience
Hersteller-Nr: E-PKSH032628

Eigenschaften

Konjugat: No
Exprimiert in: E.coli
Ursprungsart: Human
MW: 17.5 kD
Format: Lyophilized

Handhabung & Sicherheit

Lagerung: -80°C
Versand: +20°C (International: +20°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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