Insulin-Like Growth Factor 1, human recombinant, GST Tag (rHuIGF1-GST)

Insulin-Like Growth Factor 1, human recombinant, GST Tag (rHuIGF1-GST)
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Preis anfragen

Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
97305.2 2 µg - -

1 - 10 Werktage

280,00 €
97305.5 5 µg - -

1 - 10 Werktage

430,00 €
97305.10 10 µg - -

1 - 10 Werktage

780,00 €
97305.1 1 mg - -

1 - 10 Werktage

-
 
The insulin-like growth factors, isolated from plasma, are structurally and functionally related... mehr
Produktinformationen "Insulin-Like Growth Factor 1, human recombinant, GST Tag (rHuIGF1-GST)"

The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in rat bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. (www.uniprot.org) Human recombinant IGF1 produced in E.coli is a single, non-glycosylated, polypeptide chain fused to a GST tag. The somatomedins, or insulin-like growth factors (IGFs), comprise a family of peptides that play important roles in mammalian growth and development. IGF1 mediates many of the growth-promoting effects of growth hormone (GH, MIM 139250). Early studies showed that growth hormone did not directly stimulate the incorporation of sulfate into cartilage, but rather acted through a serum factor, termed sulfation factor, which later became known as somatomedin (Daughaday et al., 1972). Three main somatomedins have been characterized, somatomedin C (IGF1), somatomedin A (IGF2, MIM 147470), and somatomedin B (MIM 193190) (Rotwein, 1986, Rosenfeld, 2003).

Schlagworte: Somatomedin C, IGF-I, IGFI, IGF1, IGF-IA, Mechano growth factor, MGF
Hersteller: Biomol GmbH
Hersteller-Nr: 97305.1

Eigenschaften

Anwendung: Bioassay
Konjugat: No
Exprimiert in: E.coli
Ursprungsart: Human
Format: Purified

Datenbank Information

KEGG ID : K05459 | Finde Alternativen
UniProt ID : P05019 | Finde Alternativen

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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