Human Galectin-3

Human Galectin-3
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
ABE-32-12080-50 50 µg - -

2 - 11 Werktage

435,00 €
ABE-32-12080-100 100 µg - -

2 - 11 Werktage

599,00 €
 
Source: Genetically modified E.coli. Predicted MW: Monomer, 26.2 kDa (250 aa) Galectin-3 belongs... mehr
Produktinformationen "Human Galectin-3"
Source: Genetically modified E.coli. Predicted MW: Monomer, 26.2 kDa (250 aa) Galectin-3 belongs to the lectin family of carbohydrate binding proteins. Galectin-3 is expressed by a wide range of cell types including activated T cells, tumor cells, macrophages, osteoclasts, fibroblasts, and epithelial cells. Galectin-3 has specific binding affinity for beta-galactoside sugar moieties and has functional roles during development, innate immunity, cell apoptosis, and tumor metastasis. Galectin-3 is associated with cancer, heart failure, stroke, and inflammation. The amino acid sequences of human and mouse Galectin-3 proteins share 80% homology. Protein function: Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis. In the nucleus: acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells. [The UniProt Consortium]
Hersteller: Abeomics
Hersteller-Nr: 32-12080

Eigenschaften

Konjugat: No
Format: Lyophilized

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +20°C (International: +20°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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