Granulocyte Colony Stimulating Factor, human recombinant (rHuG-CSF)

Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. This CSF induces granulocytes. (www.uniprot.org) Produced in E.coli. Single, non-glycosylated, polypeptide chain containing 175 amino acids. The ED50, calculated by the dose-dependant proliferation of murine NFS-60 indicator cells (measured by 3H-thymidine uptake) is < 0.1 ng/ml.