Ciliary neurotrophic factor, active (CNTF), Recombinant, Human

CNTF is a survival factor for various neuronal cell types. Seems to prevent the degeneration of motor axons after axotomy. Biological Activity: Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using human TF-1 cells is less than 150ng/ml, corresponding to a specific activity of ? 6.7x10e3 IU/mg. Sequence: MAFTEHSPLT PHRRDLCSRS IWLARKIRSD LTALTESYVK HQGLNKNINL DSADGMPVAS TDQWSELTEA ERLQENLQAY RTFHVLLARL LEDQQVHFTP TEGDFHQAIH TLLLQVAAFA YQIEELMILL EYKIPRNEAD GMPINVGDGG LFEKKLWGLK VLQELSQWTV RSIHDLRFIS SHQTGIPARG SHYIANNKKM, Molecular Weight: 22.9kD, PubMed ID: 1861138, 1915374, 1840538, 1883844, 8075647, 14702039, 15489334, 7796798, 10e391209, Gene Name: CNTF, Swiss Prot: P26441, Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.