C-X-C Motif Chemokine 6/CXCL6 (C-6His) (recombinant human)

C-X-C Motif Chemokine 6/CXCL6 (C-6His) (recombinant human)
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
E-PKSH033901.10 10 µg -

7 - 16 Werktage*

242,00 €
E-PKSH033901.50 50 µg -

7 - 16 Werktage*

725,00 €
 
Protein Construction: Recombinant Human C-X-C Motif Chemokine 6 is produced by our Mammalian... mehr
Produktinformationen "C-X-C Motif Chemokine 6/CXCL6 (C-6His) (recombinant human)"
Protein Construction: Recombinant Human C-X-C Motif Chemokine 6 is produced by our Mammalian expression system and the target gene encoding Gly38-Asn114 is expressed with a 6His tag at the C-terminus. Sequence: Gly38-Asn114. Fusion tag: C-6His Endotoxin: < 1.0 EU per µg as determined by the LAL method. Apparent Molecular Mass: 13 kDa. Protein function: Chemokine (C-X-C-Motif) Ligand 6 (CXCL6) is a small cytokine belonging to the CXC chemokine family. It is a potent neutrophil chemotactic and activating factor and it exhibits extensive similarity to other CXC chemokines such as IL-8 and ENA-78. CXCL6 can promote the release of MMP-9 from granulocytes indicating its potential role as an inflammatory mediator. It functionally uses both of the IL-8/CXCL8 receptors to chemoattract neutrophils but that is structurally most related to epithelial cell-derived neutrophil attractant-78 (ENA-78)/CXCL5. The human CXCL6 gene has been cloned and is physically mapped to the CXC chemokine locus on chromosome 4. Mature human CXCL6 is a 75 amino acid (aa) protein with a predicted molecular weight of approximately 8 kDa. Human CXCL6 shares 60% and 67% aa identity with mouse and bovine CXCL6, respectively. Protein function: Chemotactic for neutrophil granulocytes. Signals through binding and activation of its receptors (CXCR1 and CXCR2). In addition to its chemotactic and angiogenic properties, it has strong antibacterial activity against Gram-positive and Gram-negative bacteria (90-fold-higher when compared to CXCL5 and CXCL7). [The UniProt Consortium]
Schlagworte: GCP2, CXCL6, Recombinant Human C-X-C Motif Chemokine 6/CXCL6 (C-6His)
Hersteller: Elabscience
Hersteller-Nr: E-PKSH033901

Eigenschaften

Konjugat: No
Wirt: Human cells
Spezies-Reaktivität: human
MW: 9.35 kD
Format: Lyophilized

Handhabung & Sicherheit

Lagerung: -80°C
Versand: 4°C (International: -20°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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