BD4, Recombinant, Human (Defensin, beta 104, HBD-4, BD-4, Beta-defensin 104, Beta-defensin 4, DEFB-4

BD4, Recombinant, Human (Defensin, beta 104, HBD-4, BD-4, Beta-defensin 104, Beta-defensin 4, DEFB-4
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
B0903-26C.20 20 µg - -

1 - 19 Werktage

406,00 €
 
Defensins are cationic peptides with a large spectrum of antimicrobial activity that comprise an... mehr
Produktinformationen "BD4, Recombinant, Human (Defensin, beta 104, HBD-4, BD-4, Beta-defensin 104, Beta-defensin 4, DEFB-4"
Defensins are cationic peptides with a large spectrum of antimicrobial activity that comprise an important arm of the innate immune system. The Alpha defensins are differentiated from the Beta-defensins by the pairing of their 3 disulfide bonds. Four human Beta-defensins have been identified to date, BD-1, BD-2, BD-3 and BD-4. Beta-defensins are expressed on some leukocytes and at epithelial surfaces. In addition to their direct antimicrobial activities, they are chemoattractant towards immature dendritic cells and memory T cells. Beta-defensin proteins are expressed as the C-terminal portion of precursors and are released by proteolytic cleavage of a signal sequence (for BD-1 a propeptide region). Beta-defensins contain a six-cysteine motif that forms three intra-molecular disulfide bonds. Beta Defensin-4 Human Recombinant produced in E. coli is a single, non-glycosylated polypeptide chain containing 50aa. The BD-4 is purified by proprietary chromatographic techniques. Recombinant protein corresponding to human BD-4, expressed in E. coli. , AA Sequence:, EFELDRICGY GTARCRKKCR SQEYRIGRCP NTYACCLRKW DESLLNRTKP, Molecular Weight: ~6kD, Biological Activity: Determined by its ability to chemoattract human monocytes using a concentration range of 0.1-50ng/ml. Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Schlagworte: BD-4, hBD-4, DEFB-4, DEFB104, DEFB104A, Beta-defensin 4, Beta-defensin 104, Defensin, beta 104
Hersteller: United States Biological
Hersteller-Nr: B0903-26C

Eigenschaften

Konjugat: No
Format: Highly Purified

Datenbank Information

UniProt ID : Q8WTQ1 | Finde Alternativen
Gene ID GeneID 140596 | Finde Alternativen

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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