BAFF, Soluble (mouse) (rec.)

BAFF, Soluble (mouse) (rec.)
%
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Rabatt Preis
AG-40B-0022-C010 10 µg -

3 - 9 Werktage*

10 %
198,00 €
178,20 €
AG-40B-0022-3010 30 µg (3 x 10 µg) -

3 - 9 Werktage*

10 %
396,00 €
356,40 €
 
Binds to human and mouse BAFF-R, TACI and BCMA. BAFF is mainly produced by innate immune cells... mehr
Produktinformationen "BAFF, Soluble (mouse) (rec.)"
Binds to human and mouse BAFF-R, TACI and BCMA. BAFF is mainly produced by innate immune cells such as neutrophils, monocytes, macrophages, dendritic cells, follicular dendritic cells. T cells, activated B cells, some malignant B cells and also non-lymphoid cells like astrocytes, synoviocytes and epithelial cells can also produce BAFF. BAFF binds three distinct receptors (BAFF-R, TACI and BCMA) expressed predominantly on B cells, although activated T cells also express BAFF-R. BAFF is a master regulator of peripheral B cell survival, and together with IL-6, promotes Ig class-switching and plasma cell differentiation. Besides its major role in B cell biology, BAFF co-stimulates activated T cells. Deregulated expression of BAFF leads to autoimmune disorders in mice. In humans, elevated levels of soluble BAFF have been detected in the serum of patients with various autoimmune diseases such as Sjoegren syndrome, Rheumatoid arthritis (RA), Multiple sclerosis (MS) and Systemic Lupus Erythematosus (SLE). BAFF has also increased levels in some lymphoid cancers.
Schlagworte: Tumor Necrosis Factor Ligand Superfamily Member 13B, TNFSF13B, B Cell Activating Factor, CD257
Hersteller: AdipoGen Life Sciences
Hersteller-Nr: AG-40B-0022

Eigenschaften

Anwendung: Bioassays
Konjugat: No
Wirt: Human cells
Spezies-Reaktivität: human, mouse
MW: 26 kD
Reinheit: >95%
Format: Lyophilized

Datenbank Information

KEGG ID : K05476 | Passende Produkte
UniProt ID : Q9WU72 | Passende Produkte

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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