Adiponectin/ACRP30/ADIPOQ Protein(C-6His) (recombinant human)

Adiponectin/ACRP30/ADIPOQ Protein(C-6His) (recombinant human)
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
E-PKSH032046.10 10 µg - -

7 - 16 Werktage

108,00 €
E-PKSH032046.50 50 µg - -

7 - 16 Werktage

289,00 €
 
Protein Construction: Recombinant Human Adipocyte complement-related 30 kDa protein is produced... mehr
Produktinformationen "Adiponectin/ACRP30/ADIPOQ Protein(C-6His) (recombinant human)"
Protein Construction: Recombinant Human Adipocyte complement-related 30 kDa protein is produced by our Mammalian expression system and the target gene encoding Glu19-Asn244 is expressed with a 6His tag at the C-terminus. Sequence: Glu19-Asn244. Fusion tag: C-6His Endotoxin: < 1.0 EU per µg as determined by the LAL method. Apparent Molecular Mass: 30 kDa. Protein function: Adiponectin is a secreted protein. It is synthesized exclusively by adipocytes and secreted into plasma. Adiponectin is an important adipokine that is involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. Adiponectin Stimulates AMPK phosphorylation and activates in the liver and the skeletal muscle, enhancing glucose utilization and fatty-acid combustion. Adiponectin also antagonizes TNF-alpha by negatively regulating its expression in various tissues such as liver and macrophages, and also by counteracting its effects. It inhibits endothelial NF-kappa-B signaling through a cAMP-dependent pathway. Adiponectin may play a role in cell growth, angiogenesis and tissue remodeling by binding and sequestering various growth factors with distinct binding affinities, depending on the type of complex: LMW, MMW or HMW. Protein function: Important adipokine involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. Stimulates AMPK phosphorylation and activation in the liver and the skeletal muscle, enhancing glucose utilization and fatty-acid combustion. Antagonizes TNF-alpha by negatively regulating its expression in various tissues such as liver and macrophages, and also by counteracting its effects. Inhibits endothelial NF-kappa-B signaling through a cAMP-dependent pathway. May play a role in cell growth, angiogenesis and tissue remodeling by binding and sequestering various growth factors with distinct binding affinities, depending on the type of complex, LMW, MMW or HMW. [The UniProt Consortium]
Schlagworte: apM-1, ADIPOQ, ACRP30, Adiponectin, Gelatin-binding protein, 30 kDa adipocyte complement-related protein, Adipocyte complement-related 30 kDa protein, Adipose most abundant gene transcript 1 protein, Adipocyte, C1q and collagen domain-containing protein,
Hersteller: Elabscience
Hersteller-Nr: PKSH032046-10µg

Eigenschaften

Konjugat: No
Exprimiert in: Human cells
Ursprungsart: Human
MW: 25.6 kD
Format: Lyophilized

Handhabung & Sicherheit

Lagerung: -80°C
Versand: +20°C (International: +20°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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globular AC-30 globular AC-30
5.197,00 €
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