Zytokine

In dieser Kategorie finden Sie extrazelluläre Signalproteine und Peptide wie Interferone (IFN), Interleukine (IL), Kolonie-stimulierende Faktoren (CSF), Tumornekrosefaktoren (TNF), Chemokine sowie Wachstumsfaktoren für Ihre Forschungsanwendungen. Zytokine regulieren die Differenzierung, Proliferation und Aktivität von Zellen und werden aus diesem Grund häufig in der Zellkultur eingesetzt. Eine weitere Funktion haben Zytokin-Produkte als Kontrollen in Immunassays. Informationen wie die spezifische Aktivität eines Zytokins, die Aminosäurensequenz, Ergebnisse eines Monozyten-Aktivierung-Tests und mehr finden Sie in den Datenblättern der Produkte.

In dieser Kategorie finden Sie extrazelluläre Signalproteine und Peptide wie Interferone (IFN), Interleukine (IL), Kolonie-stimulierende Faktoren (CSF), Tumornekrosefaktoren (TNF), Chemokine sowie... mehr erfahren »
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Zytokine

In dieser Kategorie finden Sie extrazelluläre Signalproteine und Peptide wie Interferone (IFN), Interleukine (IL), Kolonie-stimulierende Faktoren (CSF), Tumornekrosefaktoren (TNF), Chemokine sowie Wachstumsfaktoren für Ihre Forschungsanwendungen. Zytokine regulieren die Differenzierung, Proliferation und Aktivität von Zellen und werden aus diesem Grund häufig in der Zellkultur eingesetzt. Eine weitere Funktion haben Zytokin-Produkte als Kontrollen in Immunassays. Informationen wie die spezifische Aktivität eines Zytokins, die Aminosäurensequenz, Ergebnisse eines Monozyten-Aktivierung-Tests und mehr finden Sie in den Datenblättern der Produkte.

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Vascular Endothelial Growth Factor-165, human recombinant  (rHuVEGF-165-HEK)
Vascular Endothelial Growth Factor-165, human recombinant...

Artikelnummer: 97324.10

Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. NRP1/Neuropilin-1 binds...
Schlagworte: Vascular endothelial growth factor A, VEGF-A, Vascular permeability factor, VPF, VEGF, MGC70609
Anwendung: Cell Culture
Exprimiert in: Human cells
Ursprungsart: human
MW: 40 kD
ab 94,00 €
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Interleukin-1 beta, human recombinant (rHuIL-1-beta)
Interleukin-1 beta, human recombinant (rHuIL-1-beta)

Artikelnummer: 94886.10

Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release...
Schlagworte: Catabolin, Lymphocyte-activating factor (LAF), Endogenous Pyrogen (EP), Leukocyte Endogenous Mediator (LEM), Mononuclear...
Anwendung: Cell biology studies
Exprimiert in: E.coli
Ursprungsart: human
MW: 17.0 kD
ab 94,00 €
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Activin-A, active, human recombinant
Activin-A, active, human recombinant

Artikelnummer: 97394.10

Human recombinant Activin-A, active form, produced in E.coli is a homodimeric, non-glycosylated, polypeptide chain containing 2 x 117 amino acids and having a molecular weight of 26.2kDa. Activins are homodimers or heterodimers of the different beta subunit isoforms, part of the TGFbeta family. Mature Activin A has...
Schlagworte: Inhba, Inhibin beta A, FSH releasing protein.
Anwendung: Cell Culture
Exprimiert in: E.coli
Ursprungsart: human
MW: 26.2 kD
ab 94,00 €
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Vascular Endothelial Growth Factor-165, human recombinant (rHuVEGF-165)
Vascular Endothelial Growth Factor-165, human recombinant...

Artikelnummer: 87399.10

Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. NRP1/Neuropilin-1 binds...
Schlagworte: Vascular endothelial growth factor A, VEGF-A, Vascular permeability factor, VPF, VEGF, MGC70609
Anwendung: Cell Culture
Exprimiert in: E.coli
Ursprungsart: human
MW: 38.2 kD
ab 94,00 €
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Brain Derived Neurotrophic Factor, human recombinant (rHuBDNF)
Brain Derived Neurotrophic Factor, human recombinant...

Artikelnummer: 52615.10

During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses...
Schlagworte: BDNF, MGC34632
Anwendung: Cell culture
Exprimiert in: E.coli
Ursprungsart: human
MW: 27000.00 D
ab 94,00 €
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Tumor Necrosis Factor alpha, mouse recombinant (rmTNF-a)
Tumor Necrosis Factor alpha, mouse recombinant (rmTNF-a)

Artikelnummer: 52624.5

Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain...
Schlagworte: TNF-alpha, Tumor necrosis factor ligand superfamily member 2, TNF-a, Cachectin, DIF, TNFA, TNFSF2
Anwendung: Cell culture
Exprimiert in: E.coli
Ursprungsart: mouse
MW: 17.3 kD
ab 94,00 €
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TNF-beta (human, recombinant)
TNF-beta (human, recombinant)

Artikelnummer: Cay40210-1

TNF-beta, also known as lymphotoxin-alpha (LT-alpha), is a cytokine and member of the TNF and TNF receptor (TNFR) cytokine superfamily. It is produced as an N-glycosylated peptide that forms soluble bell-shaped homotrimers after signal peptide cleavage. TNF-beta also forms cell surface-anchored heterotrimers with...
Schlagworte: LTA, TNFB, LT-alpha, TNF-beta, LT-alpha, TNF-beta, Lymphotoxin-alpha, Lymphotoxin-alpha, Tumor necrosis factor ligand...
Anwendung: Active
ab 467,00 €
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Lymphotoxin-beta (cynomolgus monkey, recombinant)
Lymphotoxin-beta (cynomolgus monkey, recombinant)

Artikelnummer: Cay40211-50

Lymphotoxin-beta (LT-beta), also known as TNF-C, is a member of the TNF and TNF receptor (TNFR) cytokine superfamily. It is a type II transmembrane protein that forms heterotrimers with TNF-beta, also known as LT-alpha, which bind to the LT-beta receptor (LT-betaR). LT-beta is expressed in T cells, natural killer...
Schlagworte: LTB, LT-beta, Lymphotoxin-beta, Tumor necrosis factor C, Tumor necrosis factor ligand superfamily member 3
399,00 €
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Soluble Fas Ligand/CD95 Ligand (human, recombinant, aa 134-281)
Soluble Fas Ligand/CD95 Ligand (human, recombinant, aa...

Artikelnummer: Cay40212-1

Fas ligand (FasL), also known as CD95L, is a type II transmembrane protein and member of the TNF superfamily. It is composed of a cytoplasmic domain, transmembrane domain, stalk region, TNF homology domain (THD), which is involved in homotrimerization, and Fas-binding domain. FasL is expressed in activated T cells,...
Schlagworte: APL, SPA, APTL, FasL, FASLG, CD178, sFasL, CD95-L, APT1LG1, FasL ICD, Fas ligand, CD95 ligand, Fas antigen ligand, Soluble...
Anwendung: Active
ab 319,00 €
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Sonic HedgeHog, human recombinant (rHuSHH)
Sonic HedgeHog, human recombinant (rHuSHH)

Artikelnummer: 97290.25

Binds to the patched (PTC) receptor, which functions in association with smoothened (SMO), to activate the transcription of target genes. In the absence of SHH, PTC represses the constitutive signaling activity of SMO. Also regulates another target, the gli oncogene. Intercellular signal essential for a variety of...
Schlagworte: SHH, HHG-1, HHG1, Sonic hedgehog protein, TPT, HLP3, HPE3, SMMCI, TPTPS, MCOPCB5
Anwendung: Cell culture
Exprimiert in: E.coli
Ursprungsart: human
MW: 19683 D
ab 94,00 €
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Stromal Cell-Derived Factor-1 alpha (CXCL12), human recombinant (rHuSDF-1a)
Stromal Cell-Derived Factor-1 alpha (CXCL12), human...

Artikelnummer: 94842.10

Chemoattractant active on T-lymphocytes, monocytes, but not neutrophils. Activates the C-X-C chemokine receptor CXCR4 to induce a rapid and transient rise in the level of intracellular calcium ions and chemotaxis. SDF-1-beta(3-72) and SDF-1-alpha(3-67) show a reduced chemotactic activity. Binding to cell surface...
Schlagworte: SDF-1, CXCL12, Pre-B cell growth-stimulating factor, PBSF, hIRH, chemokine (C-X-C motif) ligand 12, SDF1, SDF1A, TPAR1,...
Anwendung: Chemoattract.
Exprimiert in: E.coli
Ursprungsart: human
MW: 8004.00 D
ab 94,00 €
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Progranulin (human) (rec.) (untagged)
Progranulin (human) (rec.) (untagged)

Artikelnummer: AG-40A-0188Y-C050

Signal peptide and human progranulin (aa 1-593) is untagged. Reflects the native sequence with no additional aa. Activates phospho-ERK1/2 in neuronal mouse P19 cells. Regulates food intake and body weight. Progranulin (PGRN) is a widely expressed pluripotent growth factor which plays a role in processes such as...
Schlagworte: GRN, Proepithelin, PEPI, PC Cell-derived Growth Factor
Anwendung: Cell culture
Exprimiert in: Human cells
Ursprungsart: human
MW: 74 kD
ab 215,00 €
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