TFPI-2 domain 1 (AGV 212 Trypsin Inhibitor), active, human recombinant & bio-clean

Active human recombinant protein expressed in non-transgenic plants. Protease inhibitor peptide generated from the first Kunitz domain of the human Tissue Factor Protein Inhibitor 2 (TFPI-2) protein, after site-directed mutagenesis to increase its activity. Recombinant AGV212 includes a 6 His-tag at the N-terminal end, is purified by sequential chromatography (FPLC). This product contains no animal-derived components or impurities. Inhibits trypsin with high efficiency and Ki lower than TFPI-2 alone. TFPI-2 has been shown to inhibit Endothelial Cell Matrix (ECM) proteases essential for angiogenesis and metastasis. One mg protein will inhibit 1-1.5 mg trypsin with activity of approximately 10,000 BAEE units per mg protein.