SIRP alpha V5 Protein, Human, Recombinant (His & Avi)," Biotinylated

Description: Signal regulatory protein alpha (SIRPalpha) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPalpha acts as inhibitory receptor and interacts with a broadly expressed transmembrane protein CD47 also called the """"don Ì?t eat me"""" signal.Cancer cells highly expressed CD47 that activate SIRP alpha and inhibit macrophage-mediated destruction. SIRP alpha V5 Protein", Human, Recombinant (His & Avi)," Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 40 kDa and the accession number is P78324 variant 5.""