SARS-CoV-2 Spike Protein S1 (RBD):Fc (h) (rec.) (gamma P.1 Variant, BR)

SARS-CoV-2 Spike Protein S1 (RBD):Fc (h) (rec.) (gamma P.1 Variant, BR)
%
COVID-19 Forschung
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Rabatt Preis
AG-40B-0204-C050 50 µg -

3 - 9 Werktage*

10 %
341,00 €
306,90 €
AG-40B-0204-3050 150 µg (3 x 50 µg) -

3 - 9 Werktage*

10 %
682,00 €
613,80 €
 
SARS-CoV-2 shares 79.5% sequence identity with SARS-CoV and is 96.2% identical at the genome... mehr
Produktinformationen "SARS-CoV-2 Spike Protein S1 (RBD):Fc (h) (rec.) (gamma P.1 Variant, BR)"
SARS-CoV-2 shares 79.5% sequence identity with SARS-CoV and is 96.2% identical at the genome level to the bat coronavirus BatCoV RaTG133, suggesting it had originated in bats. The coronaviral genome encodes four major structural proteins: the Spike (S) protein, Nucleocapsid (N) protein, Membrane/Matrix (M) protein and the Envelope (E) protein. The SARS Envelope (E) protein contains a short palindromic transmembrane helical hairpin that seems to deform lipid bilayers, which may explain its role in viral budding and virion envelope morphogenesis. The SARS Membrane/Matrix (M) protein is one of the major structural viral proteins. It is an integral membrane protein involved in the budding of the viral particles and interacts with SARS Spike (S) protein and the Nucleocapsid (N) protein. The N protein contains two domains, both of them bind the virus RNA genome via different mechanisms.The CoV Spike (S) protein assembles as trimer and plays the most important role in viral attachment, fusion and entry. It is composed of a short intracellular tail, a transmembrane anchor and a large ectodomain that consists of a receptor binding S1 subunit (RBD domain) and a membrane-fusing S2 subunit. The S1 subunit contains a receptor binding domain (RBD), which binds to the cell surface receptor angiotensin-converting enzyme 2 (ACE2) present at the surface of epithelial cells. Recently, a new variant of SARS-CoV-2, called P.1 was detected in Brazil. This variant carries three mutations in the RBD at the positions 417, 484 and 501 (K417T, E484K, N501Y). The P.1 or Brazilian variant is a form of the SARS-CoV-2 coronavirus that appears to have evolved in Brazil and might have contributed to a surge in cases in the northern city of Manaus.
Schlagworte: 2019-nCoV Spike Protein S1 (RBD), Spike Receptor Binding Domain Variant Brasil, B.1.1.248, 20J/501Y.V3, VOC-202101/02
Hersteller: AdipoGen Life Sciences
Hersteller-Nr: AG-40B-0204

Eigenschaften

Konjugat: No
Wirt: Human cells
Spezies-Reaktivität: SARS-CoV-2
MW: 60 kD
Reinheit: >95% (SDS-PAGE)
Format: Lyophilized

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
Hier kriegen Sie ein Zertifikat
oder , um Analysenzertifikate anzufordern.
Bewertungen lesen, schreiben und diskutieren... mehr
Kundenbewertungen für "SARS-CoV-2 Spike Protein S1 (RBD):Fc (h) (rec.) (gamma P.1 Variant, BR)"
Bewertung schreiben
oder , um eine Produktbewertung abzugeben.
Zuletzt angesehen