Recombinant Rat SCF/c-Kit Ligand Protein (Human Cells, His Tag) (RPES4293)

Recombinant Rat SCF/c-Kit Ligand Protein (Human Cells, His Tag) (RPES4293)
NEU
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
G-RPES4293.10 10 µg - - -

9 - 20 Werktage*

206,00 €
 
Recombinant Rat SCF/c-Kit Ligand Protein (Human Cells, His Tag) from Assay Genie. Recombinant Rat... mehr
Produktinformationen "Recombinant Rat SCF/c-Kit Ligand Protein (Human Cells, His Tag) (RPES4293)"
Recombinant Rat SCF/c-Kit Ligand Protein (Human Cells, His Tag) from Assay Genie. Recombinant Rat SCF/c-Kit Ligand Protein (Human Cells, His Tag) is a highly purified recombinant protein produced in Human Cells and for the use in functional assays from Assay Genie.. Protein function: Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. KITLG/SCF binding can activate several signaling pathways. Promotes phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, and subsequent activation of the kinase AKT1. KITLG/SCF and KIT also transmit signals via GRB2 and activation of RAS, RAF1 and the MAP kinases MAPK1/ERK2 and/or MAPK3/ERK1. KITLG/SCF and KIT promote activation of STAT family members STAT1, STAT3 and STAT5. KITLG/SCF and KIT promote activation of PLCG1, leading to the production of the cellular signaling molecules diacylglycerol and inositol 1,4,5-trisphosphate. KITLG/SCF acts synergistically with other cytokines, probably interleukins. [The UniProt Consortium]
Schlagworte: Kitl, Kitlg
Hersteller: Assay Genie
Hersteller-Nr: RPES4293

Eigenschaften

Konjugat: No
Exprimiert in: Human cells
Format: Highly Purified

Datenbank Information

KEGG ID : K05461 | Passende Produkte
UniProt ID : P21581 | Passende Produkte

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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