Recombinant Mouse TYRO3/DTK Protein (mFc Tag) (RPES3655)

Recombinant Mouse TYRO3/DTK Protein (mFc Tag) (RPES3655)
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
G-RPES3655.10 10 µg - - -

9 - 20 Werktage*

71,00 €
Recombinant Mouse TYRO3/DTK Protein (mFc Tag) from Assay Genie. Recombinant Mouse TYRO3/DTK... mehr
Produktinformationen "Recombinant Mouse TYRO3/DTK Protein (mFc Tag) (RPES3655)"
Recombinant Mouse TYRO3/DTK Protein (mFc Tag) from Assay Genie. Recombinant Mouse TYRO3/DTK Protein (mFc Tag) is a highly purified recombinant protein produced in Human Cells and for the use in functional assays from Assay Genie.. Protein function: Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to several ligands including TULP1 or GAS6. Regulates many physiological processes including cell survival, migration and differentiation. Ligand binding at the cell surface induces dimerization and autophosphorylation of TYRO3 on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with PIK3R1 and thereby enhances PI3-kinase activity. Activates the AKT survival pathway, including nuclear translocation of NF-kappa-B and up-regulation of transcription of NF-kappa-B-regulated genes. TYRO3 signaling plays a role in various processes such as neuron protection from excitotoxic injury, platelet aggregation and cytoskeleton reorganization. Plays also an important role in inhibition of Toll-like receptors (TLRs)-mediated innate immune response by activating STAT1, which selectively induces production of suppressors of cytokine signaling SOCS1 and SOCS3. [The UniProt Consortium]
Schlagworte: Dtk, Tyro3, TK19-2, Etk2/tyro3, EC=, Tyrosine-protein kinase RSE, Tyrosine-protein kinase TIF, Tyrosine-protein kinase DTK, Tyrosine-protein kinase receptor TYRO3
Hersteller: Assay Genie
Hersteller-Nr: RPES3655


Konjugat: No
Exprimiert in: Human cells
Ursprungsart: Mouse
Format: Highly Purified

Datenbank Information

KEGG ID : K05116 | Passende Produkte
UniProt ID : P55144 | Passende Produkte

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +4°C (International: +4°C)
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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